SCHEMBL9568792

SCHEMBL9568792

C=CC(=O)Nc1ccc(NS(=O)(=O)c2ccc(C)cc2)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.71
POLB P06746 1/20 0.71
TGM2 P21980 2/20 0.71
KMT2A Q03164 5/20 0.60
LMNA P02545 4/20 0.60
MEN1 O00255 4/20 0.60
SMN1; SMN2 Q16637 2/20 0.60
ALOX12 P18054 1/20 0.60
RECQL P46063 1/20 0.60
HSD17B10 Q99714 1/20 0.60
MAPT P10636 4/20 0.60
HPGD P15428 2/20 0.60
HDAC4 P56524 2/20 0.59
HDAC1 Q13547 2/20 0.59
GLA P06280 1/20 0.59
CRHBP P24387 1/20 0.59
HTT P42858 1/20 0.59
CRHR2 Q13324 1/20 0.59
HDAC8 Q9BY41 1/20 0.59
SNCA P37840 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3821674 1.00 ALDH1A1 (0.71) ALDH1A1POLBTGM2KMT2ALMNA
SCHEMBL3820009 0.87 TGM2 (0.67) ALDH1A1POLBTGM2KMT2AMEN1
SCHEMBL19457348 0.86 TGM2 (0.77) ALDH1A1POLBTGM2KMT2ALMNA
SCHEMBL9568733 0.86 BTK (0.63) ALDH1A1POLBTGM2KMT2ALMNA
SCHEMBL14394824 0.86 ALDH1A1 (0.65) ALDH1A1POLBTGM2KMT2ALMNA
SCHEMBL14394819 0.85 CES1 (0.65) ALDH1A1POLBTGM2KMT2ALMNA
SCHEMBL17240362 0.85 TGM2 (0.57) ALDH1A1POLBTGM2KMT2ALMNA
SCHEMBL9568604 0.85 TGM2 (0.64) ALDH1A1POLBTGM2KMT2AMEN1
SCHEMBL23988634 0.85 TGM2 (0.58) ALDH1A1POLBTGM2KMT2ALMNA
SCHEMBL648950 0.84 TGM2 (1.00) ALDH1A1POLBTGM2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0544264-A1 Light-sensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1993-06-02 EP disclosed