SCHEMBL3821691

SCHEMBL3821691

CC(C)c1ccc(-c2[c]c(-c3ccc(C(C)C)cc3)ccc2)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.37
NPC1 O15118 2/20 0.37
NOTUM Q6P988 2/20 0.37
TP53 P04637 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
MAPT P10636 2/20 0.37
PAX8 Q06710 1/20 0.37
NOD2 Q9HC29 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
MEN1 O00255 1/20 0.37
USP2 O75604 1/20 0.37
LMNA P02545 1/20 0.37
KMT2A Q03164 1/20 0.37
TYR P14679 2/20 0.37
KDM4E B2RXH2 1/20 0.36
HPGD P15428 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
NISCH Q9Y2I1 1/20 0.36
KIF11 P52732 1/20 0.36
PTPN5 P54829 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3817728 0.82 CYP2C9 (0.38) RAB9ANPC1NOTUMTP53NPSR1
SCHEMBL3818485 0.80 KIF11 (0.39) RAB9ANPC1NOTUMTP53NPSR1
SCHEMBL3819772 0.78 LMNA (0.38) RAB9ANPC1NOTUMTP53NPSR1
SCHEMBL27454631 0.78 MEN1 (0.31) MAPTMEN1USP2LMNAKMT2A
SCHEMBL597362 0.78 PTPN5 (0.49) RAB9ANPC1NOTUMTP53NPSR1
SCHEMBL1371593 0.77 TNKS (0.38) RAB9ANPC1NOTUMTP53NPSR1
SCHEMBL197335 0.74 KIF11 (0.52) RAB9ANPC1NOTUMTP53NPSR1
SCHEMBL3816568 0.74 PTPN5 (0.37) RAB9ANPC1NOTUMTP53NPSR1
SCHEMBL2774036 0.73 ACHE (0.42) RAB9ANPC1NPSR1MAPTL3MBTL1
SCHEMBL28026885 0.72 IDO1 (0.39) RAB9ANPC1NOTUMTP53NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10381579-B2 Stability OLED materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-08-13 US claimed
US-20150249225-A1 STABILITY OLED MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-09-03 US claimed
US-9051344-B2 Stability OLED materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2015-06-09 US claimed
EP-1878053-B1 STABILITY OLED MATERIALS AND DEVICES WITH IMPROVED STABILITY UNIVERSAL DISPLAY CORP (US) 2009-08-26 EP claimed
US-11404650-B2 Stability OLED materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-08-02 US disclosed
US-10381579-B2 Stability OLED materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-08-13 US disclosed
CN-107011388-A Stability OLED materials and the device with improved stability 通用显示公司 2017-08-04 CN disclosed
US-20150249225-A1 STABILITY OLED MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-09-03 US disclosed
CN-101180304-B Stable OLED materials and devices with improved stability UNIVERSAL DISPLAY CORP. (US) 2015-08-19 CN disclosed
US-9051344-B2 Stability OLED materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2015-06-09 US disclosed
US-7902374-B2 Stability OLED materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2011-03-08 US disclosed
EP-1878053-B1 STABILITY OLED MATERIALS AND DEVICES WITH IMPROVED STABILITY UNIVERSAL DISPLAY CORP (US) 2009-08-26 EP disclosed
WO-2008054584-A1 IMPROVED STABILITY OLED MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2008-05-08 WO disclosed
EP-1878053-A1 STABILITY OLED MATERIALS AND DEVICES WITH IMPROVED STABILITY Universal Display Corporation (US) 2008-01-16 EP disclosed
US-20070088167-A1 Stability OLED materials and devices UNIVERSAL DISPLAY CORPORATION 2007-04-19 US disclosed
WO-2006121811-A1 STABILITY OLED MATERIALS AND DEVICES WITH IMPROVED STABILITY UNIVERSAL DISPLAY CORPORATION (US) 2006-11-16 WO disclosed
US-20060251923-A1 Stability OLED materials and devices UNIVERSAL DISPLAY CORPORATION 2006-11-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11404650-B2 Stability OLED materials and devices OCIAD2, OCIAD1, OSBP2 RAB9A 593/4885NPC1 205/4885NOTUM 3218/4885
US-10381579-B2 Stability OLED materials and devices OCIAD2, OCIAD1, OSBP2 RAB9A 612/4885NPC1 204/4885NOTUM 3142/4885
US-20150249225-A1 STABILITY OLED MATERIALS AND DEVICES OCIAD2, OCIAD1, OSBP2 RAB9A 612/4885NPC1 204/4885NOTUM 3142/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.