Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 6/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.34 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21801276 | 0.89 | ACHE (0.39) | ACHETDP1HPGDNPC1RAB9A | |
| SCHEMBL29104461 | 0.88 | ACHE (0.36) | ACHETDP1LMNATSHRALOX12 | |
| SCHEMBL5461557 | 0.79 | ACHE (0.42) | ACHETDP1LMNAHPGDNPC1 | |
| SCHEMBL9119298 | 0.78 | PTGS2 (0.38) | LMNAHPGDSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL4647857 | 0.75 | NPC1 (0.49) | ACHETDP1LMNATSHRALOX12 | |
| SCHEMBL379055 | 0.75 | ALDH1A1 (0.47) | TDP1LMNAHPGDNPC1RAB9A | |
| SCHEMBL28150406 | 0.74 | ALDH1A1 (0.48) | TDP1TSHRNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3822120 | 0.74 | NPC1 (0.36) | ACHENPC1RAB9ACYP2C9CYP2C19 | |
| SCHEMBL598796 | 0.74 | ACHE (0.57) | ACHETDP1LMNATSHRALOX12 | |
| SCHEMBL67548 | 0.73 | ACHE (0.38) | ACHETDP1LMNATSHRALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140330018-A1 | METATHESIS CATALYSTS AND METHODS THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2014-11-06 | — | — | US | claimed |
| US-7642324-B2 | Methods of using heterocycle-amine ligands, compositions, complexes, and catalysts | SYMYX SOLUTIONS, INC. (US) | 2010-01-05 | — | — | US | claimed |
| US-7642216-B2 | Methods of using heterocycle-amine ligands, compositions, complexes, and catalysts | SYMYX SOLUTIONS, INC. (US) | 2010-01-05 | — | — | US | claimed |
| US-20090143222-A1 | METHODS OF USING HETEROCYCLE-AMINE LIGANDS, COMPOSITIONS, COMPLEXES, AND CATALYSTS | SYMYX TECHNOLOGIES, INC. (US) | 2009-06-04 | — | — | US | claimed |
| US-20090131619-A1 | METHODS OF USING HETEROCYCLE-AMINE LIGANDS, COMPOSITIONS, COMPLEXES, AND CATALYSTS | SYMYX TECHNOLOGIES, INC. (US) | 2009-05-21 | — | — | US | claimed |
| US-6916893-B2 | Polymerization-active transition metal complexes having bulky ligand systems | SER. V. GMBH (DE) | 2005-07-12 | — | — | US | claimed |
| US-20040171774-A1 | Polymerization-active transition metal complexes having bulky ligand systems | RIEGER BERNHARD (DE) | 2004-09-02 | — | — | US | claimed |
| US-20140330018-A1 | METATHESIS CATALYSTS AND METHODS THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2014-11-06 | — | — | US | disclosed |
| US-7902374-B2 | Stability OLED materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2011-03-08 | — | — | US | disclosed |
| US-7642324-B2 | Methods of using heterocycle-amine ligands, compositions, complexes, and catalysts | SYMYX SOLUTIONS, INC. (US) | 2010-01-05 | — | — | US | disclosed |
| US-7642216-B2 | Methods of using heterocycle-amine ligands, compositions, complexes, and catalysts | SYMYX SOLUTIONS, INC. (US) | 2010-01-05 | — | — | US | disclosed |
| US-20090143222-A1 | METHODS OF USING HETEROCYCLE-AMINE LIGANDS, COMPOSITIONS, COMPLEXES, AND CATALYSTS | SYMYX TECHNOLOGIES, INC. (US) | 2009-06-04 | — | — | US | disclosed |
| US-20090131619-A1 | METHODS OF USING HETEROCYCLE-AMINE LIGANDS, COMPOSITIONS, COMPLEXES, AND CATALYSTS | SYMYX TECHNOLOGIES, INC. (US) | 2009-05-21 | — | — | US | disclosed |
| EP-1794196-A2 | HETEROCYCLE-AMINE LIGANDS, COMPOSITIONS, COMPLEXES, AND CATALYSTS, AND METHODS OF MAKING AND USING THE SAME | Symyx Technologies, Inc. (US) | 2007-06-13 | — | — | EP | disclosed |
| US-20070088167-A1 | Stability OLED materials and devices | UNIVERSAL DISPLAY CORPORATION | 2007-04-19 | — | — | US | disclosed |
| US-20060094839-A1 | Methods of using heterocycle-amine ligands, compositions, complexes, and catalysts | SYMYX TECHNOLOGIES, INC. (US) | 2006-05-04 | — | — | US | disclosed |
| US-20060094867-A1 | Heterocycle-amine ligands, compositions, complexes, and catalysts | SYMYX TECHNOLOGIES, INC. (US) | 2006-05-04 | — | — | US | disclosed |
| WO-2006036748-A2 | HETEROCYCLE-AMINE LIGANDS, COMPOSITIONS, COMPLEXES, AND CATALYSTS, AND METHODS OF MAKING AND USING THE SAME | SYMYX TECHNOLOGIES, INC. (US) | 2006-04-06 | — | — | WO | disclosed |
| US-6916893-B2 | Polymerization-active transition metal complexes having bulky ligand systems | SER. V. GMBH (DE) | 2005-07-12 | — | — | US | disclosed |
| US-20040171774-A1 | Polymerization-active transition metal complexes having bulky ligand systems | RIEGER BERNHARD (DE) | 2004-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060094867-A1 | Heterocycle-amine ligands, compositions, complexes, and catalysts | PCNA, MYB, PNMT | ACHE 1417/4885TDP1 408/4885LMNA 3587/4885 |
| US-20140330018-A1 | METATHESIS CATALYSTS AND METHODS THEREOF | TERT, CYP19A1, MPO | ACHE 15/4885TDP1 1975/4885LMNA 1361/4885 |
| US-20060094839-A1 | Methods of using heterocycle-amine ligands, compositions, complexes, and catalysts | PCNA, PPOX, ODC1 | ACHE 1213/4885TDP1 282/4885LMNA 3058/4885 |
| US-20040171774-A1 | Polymerization-active transition metal complexes having bulky ligand systems | AP1M1, CCNC, CLTB | ACHE 4396/4885TDP1 3418/4885LMNA 522/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.