SCHEMBL3819772

SCHEMBL3819772

Cc1cc(-c2ccc(C(C)C)cc2)[c]c(-c2ccc(C(C)C)cc2)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.38
PTGS1 P23219 2/20 0.36
TRPA1 O75762 1/20 0.36
CACNA1C Q13936 1/20 0.36
NPC1 O15118 3/20 0.35
RAB9A P51151 3/20 0.35
NPSR1 Q6W5P4 2/20 0.35
NOTUM Q6P988 2/20 0.35
TP53 P04637 1/20 0.35
CSNK2A2 P19784 1/20 0.35
CSNK2B P67870 1/20 0.35
CSNK2A1 P68400 1/20 0.35
TYR P14679 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
KDM4E B2RXH2 2/20 0.34
HPGD P15428 1/20 0.34
NISCH Q9Y2I1 1/20 0.34
KIF11 P52732 1/20 0.34
PTGS2 P35354 1/20 0.34
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3817728 0.87 CYP2C9 (0.38) LMNAPTGS1TRPA1CACNA1CNPC1
SCHEMBL3818485 0.85 KIF11 (0.39) LMNAPTGS1TRPA1CACNA1CNPC1
SCHEMBL6915325 0.80 LMNA (0.44) LMNAPTGS1TRPA1CACNA1CNPC1
SCHEMBL5461557 0.80 ACHE (0.42) LMNANPC1RAB9ASMN1; SMN2KDM4E
SCHEMBL3816568 0.79 PTPN5 (0.37) NPC1RAB9ANPSR1NOTUMTP53
SCHEMBL3821691 0.78 RAB9A (0.37) LMNANPC1RAB9ANPSR1NOTUM
SCHEMBL28026885 0.77 IDO1 (0.39) LMNANPC1RAB9ANPSR1NOTUM
SCHEMBL3819329 0.73 RXRA (0.42) PTGS2PTPN5CYP2C9
SCHEMBL7914615 0.73 LMNA (0.41) LMNANPC1RAB9ASMN1; SMN2KDM4E
SCHEMBL840282 0.72 METAP2 (0.40) LMNAPTGS1KIF11PTGS2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10381579-B2 Stability OLED materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-08-13 US claimed
US-20150249225-A1 STABILITY OLED MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-09-03 US claimed
US-9051344-B2 Stability OLED materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2015-06-09 US claimed
EP-1878053-B1 STABILITY OLED MATERIALS AND DEVICES WITH IMPROVED STABILITY UNIVERSAL DISPLAY CORP (US) 2009-08-26 EP claimed
US-11404650-B2 Stability OLED materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-08-02 US disclosed
US-10381579-B2 Stability OLED materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-08-13 US disclosed
US-20150249225-A1 STABILITY OLED MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-09-03 US disclosed
US-9051344-B2 Stability OLED materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2015-06-09 US disclosed
US-7902374-B2 Stability OLED materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2011-03-08 US disclosed
EP-1878053-B1 STABILITY OLED MATERIALS AND DEVICES WITH IMPROVED STABILITY UNIVERSAL DISPLAY CORP (US) 2009-08-26 EP disclosed
WO-2008054584-A1 IMPROVED STABILITY OLED MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2008-05-08 WO disclosed
EP-1878053-A1 STABILITY OLED MATERIALS AND DEVICES WITH IMPROVED STABILITY Universal Display Corporation (US) 2008-01-16 EP disclosed
US-20070088167-A1 Stability OLED materials and devices UNIVERSAL DISPLAY CORPORATION 2007-04-19 US disclosed
WO-2006121811-A1 STABILITY OLED MATERIALS AND DEVICES WITH IMPROVED STABILITY UNIVERSAL DISPLAY CORPORATION (US) 2006-11-16 WO disclosed
US-20060251923-A1 Stability OLED materials and devices UNIVERSAL DISPLAY CORPORATION 2006-11-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11404650-B2 Stability OLED materials and devices OCIAD2, OCIAD1, OSBP2 LMNA 3178/4885PTGS1 4638/4885TRPA1 226/4885
US-10381579-B2 Stability OLED materials and devices OCIAD2, OCIAD1, OSBP2 LMNA 3210/4885PTGS1 4634/4885TRPA1 225/4885
US-20150249225-A1 STABILITY OLED MATERIALS AND DEVICES OCIAD2, OCIAD1, OSBP2 LMNA 3210/4885PTGS1 4634/4885TRPA1 225/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.