Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 3/20 | 0.46 |
| ▸ | DRD1 | P21728 | 3/20 | 0.46 |
| ▸ | DRD5 | P21918 | 3/20 | 0.46 |
| ▸ | DRD3 | P35462 | 3/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ME2 | P23368 | 1/20 | 0.41 |
| ▸ | ME1 | P48163 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3826601 | 0.91 | RAB9A (0.48) | RAB9ADRD2DRD3HTR1ADRD4 | |
| SCHEMBL3823112 | 0.90 | RAB9A (0.52) | L3MBTL1RAB9ADRD2DRD1DRD5 | |
| SCHEMBL8185381 | 0.89 | DRD2 (0.48) | L3MBTL1RAB9ADRD2DRD1DRD5 | |
| SCHEMBL8185382 | 0.87 | RAB9A (0.48) | L3MBTL1RAB9ADRD2DRD1DRD5 | |
| SCHEMBL8179037 | 0.86 | L3MBTL1 (0.54) | L3MBTL1RAB9ADRD2DRD1DRD5 | |
| SCHEMBL8184144 | 0.85 | L3MBTL1 (0.44) | L3MBTL1RAB9ADRD2DRD1DRD5 | |
| SCHEMBL3823072 | 0.85 | KDM4E (0.45) | L3MBTL1RAB9ADRD2DRD1DRD5 | |
| SCHEMBL3829302 | 0.83 | ALDH1A1 (0.50) | DRD2DRD1DRD5DRD3HTR1A | |
| SCHEMBL3830332 | 0.83 | MEN1 (0.45) | L3MBTL1RAB9ADRD2DRD1DRD5 | |
| SCHEMBL3827371 | 0.83 | KDM4E (0.44) | L3MBTL1RAB9ADRD2DRD1DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073936-A1 | CARBOXAMIDE DERIVATIVES AS ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | disclosed |