Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 5/20 | 0.43 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD4 | P21917 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | DRD5 | P21918 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3829727 | 0.94 | QPCT (0.43) | QPCTPDK1ALDH1A1LMNADRD2 | |
| SCHEMBL3830922 | 0.92 | L3MBTL1 (0.43) | QPCTPDK1ALDH1A1LMNATSHR | |
| SCHEMBL3824125 | 0.88 | L3MBTL1 (0.44) | TDO2PDK1DRD2DRD4DRD3 | |
| SCHEMBL3823358 | 0.88 | HTR1A (0.40) | QPCTPDK1ALDH1A1DRD2DRD4 | |
| SCHEMBL8195090 | 0.85 | L3MBTL1 (0.40) | QPCTPDK1ALDH1A1LMNADRD2 | |
| SCHEMBL3823072 | 0.85 | KDM4E (0.45) | PDK1LMNADRD2DRD4DRD3 | |
| SCHEMBL3831333 | 0.84 | HSD17B10 (0.49) | ALDH1A1TSHRHTR2AOPRM1OPRK1 | |
| SCHEMBL3823632 | 0.83 | L3MBTL1 (0.45) | TDO2ALDH1A1TSHRDRD2DRD4 | |
| SCHEMBL3825193 | 0.83 | QPCT (0.47) | QPCTALDH1A1LMNAHTR1AHTR2A | |
| SCHEMBL3827091 | 0.83 | L3MBTL1 (0.44) | PDK1ALDH1A1TSHROPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2097379-A1 | CARBOXAMIDE DERIVATIVES AS ION CHANNEL MODULATORS | Wyeth a Corporation of the State of Delaware (US) | 2009-09-09 | — | — | EP | claimed |
| WO-2008073936-A1 | CARBOXAMIDE DERIVATIVES AS ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | claimed |
| WO-2008073936-A1 | CARBOXAMIDE DERIVATIVES AS ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | disclosed |