Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.57 |
| ▸ | FAAH | O00519 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3821905 | 1.00 | ALDH1A1 (0.64) | ALDH1A1GAAMAPTEPHX2SMN1; SMN2 | |
| SCHEMBL5510217 | 1.00 | ALDH1A1 (0.64) | ALDH1A1GAAMAPTEPHX2SMN1; SMN2 | |
| SCHEMBL5508615 | 1.00 | ALDH1A1 (0.64) | ALDH1A1GAAMAPTEPHX2SMN1; SMN2 | |
| SCHEMBL3823182 | 0.97 | ALDH1A1 (0.61) | ALDH1A1GAAMAPTEPHX2SMN1; SMN2 | |
| SCHEMBL3822389 | 0.89 | ALDH1A1 (0.62) | ALDH1A1GAAMAPTEPHX2SMN1; SMN2 | |
| SCHEMBL3815751 | 0.86 | SMN1; SMN2 (0.72) | ALDH1A1GAAMAPTSMN1; SMN2LMNA | |
| SCHEMBL7134961 | 0.86 | ALDH1A1 (0.59) | ALDH1A1GAAMAPTEPHX2SMN1; SMN2 | |
| SCHEMBL22221566 | 0.85 | EPHX2 (0.71) | ALDH1A1EPHX2SMN1; SMN2CHRM2FAAH | |
| SCHEMBL344561 | 0.84 | SMN1; SMN2 (0.62) | ALDH1A1GAAMAPTSMN1; SMN2CHRM2 | |
| SCHEMBL3818872 | 0.84 | SMN1; SMN2 (0.65) | ALDH1A1GAAMAPTEPHX2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1479370-B1 | 3-Methoxybenzyl thiourea derivatives and improved lipid compositions containing same | USA (US) | 2009-07-08 | — | — | EP | claimed |
| EP-1155677-B1 | Compositions for inhibiting free radical polymerization in skin and hair | FAN TECH LTD (US) | 2007-06-13 | — | — | EP | claimed |
| EP-1280495-B1 | 3-METHOXYBENZYL THIOUREA DERIVATIVES AND IMPROVED LIPID COMPOSITIONS CONTAINING SAME | US AGRICULTURE (US) | 2006-11-22 | — | — | EP | claimed |
| US-7053243-B2 | 3-Methoxybenzyl thiourea derivatives and improved lipid compositions containing same | THE FANNING CORPORATION (US) | 2006-05-30 | — | — | US | claimed |
| EP-1479370-A1 | 3-Methoxybenzyl thiourea derivatives and improved lipid compositions containing same | The United States of America (US) | 2004-11-24 | — | — | EP | claimed |
| US-20040030188-A1 | 3-Methoxybenzyl thiourea derivatives and improved lipid compositions containing same | SECRETARY OF AGRICULTURE | 2004-02-12 | — | — | US | claimed |
| US-20030114532-A1 | Methods and compositions for inhibiting free radical polymerization in skin and hair | FAN TECH, LTD. | 2003-06-19 | — | — | US | claimed |
| US-6545052-B2 | Contacting skin with skin treatment composition having concentration of 1-(3-methoxybenzyl)-3-substituted thiourea compound effective for inhibiting free radical generation | FAN TECH, LTD. | 2003-04-08 | — | — | US | claimed |
| US-20010056205-A1 | 3-Methoxybenzyl thiourea derivatives and improved lipid compositions containing same | THE FANNING CORPORATION | 2001-12-27 | — | — | US | claimed |
| EP-1155677-A2 | Methods and compositions for inhibiting free radical polymerization in skin and hair | Fan Tech Ltd. (US) | 2001-11-21 | — | — | EP | claimed |
| EP-1155677-B1 | Compositions for inhibiting free radical polymerization in skin and hair | FAN TECH LTD (US) | 2007-06-13 | — | — | EP | disclosed |
| US-7169815-B2 | 3-methoxybenzyl thiourea derivatives and improved lipid compositions containing same | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 2007-01-30 | — | — | US | disclosed |
| US-7053243-B2 | 3-Methoxybenzyl thiourea derivatives and improved lipid compositions containing same | THE FANNING CORPORATION (US) | 2006-05-30 | — | — | US | disclosed |
| US-20040030188-A1 | 3-Methoxybenzyl thiourea derivatives and improved lipid compositions containing same | SECRETARY OF AGRICULTURE | 2004-02-12 | — | — | US | disclosed |
| US-6653505-B2 | Oxidation resistance | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE | 2003-11-25 | — | — | US | disclosed |
| US-20030114532-A1 | Methods and compositions for inhibiting free radical polymerization in skin and hair | FAN TECH, LTD. | 2003-06-19 | — | — | US | disclosed |
| US-6545052-B2 | Contacting skin with skin treatment composition having concentration of 1-(3-methoxybenzyl)-3-substituted thiourea compound effective for inhibiting free radical generation | FAN TECH, LTD. | 2003-04-08 | — | — | US | disclosed |
| US-20020147365-A1 | 3-methoxybenzyl thiourea derivatives and improved lipid compositions containing same | THE FANNING CORPORATION | 2002-10-10 | — | — | US | disclosed |
| US-20010056205-A1 | 3-Methoxybenzyl thiourea derivatives and improved lipid compositions containing same | THE FANNING CORPORATION | 2001-12-27 | — | — | US | disclosed |
| EP-1155677-A2 | Methods and compositions for inhibiting free radical polymerization in skin and hair | Fan Tech Ltd. (US) | 2001-11-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040030188-A1 | 3-Methoxybenzyl thiourea derivatives and improved lipid compositions containing same | GPX4, LIPC, GPX1 | ALDH1A1 754/4885GAA 1380/4885MAPT 4121/4885 |
| US-20010056205-A1 | 3-Methoxybenzyl thiourea derivatives and improved lipid compositions containing same | GPX4, LIPC, GPX1 | ALDH1A1 754/4885GAA 1380/4885MAPT 4121/4885 |
| US-20020147365-A1 | 3-methoxybenzyl thiourea derivatives and improved lipid compositions containing same | GPX4, LIPC, GPX1 | ALDH1A1 754/4885GAA 1380/4885MAPT 4121/4885 |
| US-20030114532-A1 | Methods and compositions for inhibiting free radical polymerization in skin and hair | TST, BHMT2, TXN2 | ALDH1A1 782/4885GAA 4700/4885MAPT 1081/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.