SCHEMBL3824015

SCHEMBL3824015

C=CC(=O)NCc1ccc(S(=O)(=O)Nc2ccc(C)cc2)cc1

nearest known ligand 0.66

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.66
TDP1 Q9NUW8 1/20 0.59
NAMPT P43490 1/20 0.59
ALDH1A1 P00352 6/20 0.57
POLB P06746 2/20 0.55
MAPT P10636 2/20 0.54
HPGD P15428 1/20 0.53
HDAC4 P56524 2/20 0.53
HDAC1 Q13547 2/20 0.53
HDAC8 Q9BY41 1/20 0.53
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
RECQL P46063 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
HSD17B10 Q99714 1/20 0.51
USP2 O75604 1/20 0.51
GHSR Q92847 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL395033 1.00 LMNA (0.66) LMNATDP1NAMPTALDH1A1POLB
SCHEMBL7784363 0.88 ALDH1A1 (0.54) LMNANAMPTALDH1A1POLBMAPT
SCHEMBL397470 0.87 ALDH1A1 (0.56) LMNATDP1NAMPTALDH1A1HDAC4
SCHEMBL396618 0.87 ALDH1A1 (0.56) LMNANAMPTALDH1A1MAPTHDAC4
SCHEMBL397234 0.85 MEN1 (0.56) LMNANAMPTALDH1A1POLBHDAC4
SCHEMBL959540 0.83 TGM2 (0.69) LMNAALDH1A1MAPTHPGDMEN1
SCHEMBL9568792 0.82 ALDH1A1 (0.71) LMNAALDH1A1POLBMAPTHPGD
SCHEMBL3821674 0.82 ALDH1A1 (0.71) LMNAALDH1A1POLBMAPTHPGD
SCHEMBL8995939 0.82 TGM2 (0.59) LMNAALDH1A1MAPTHPGDMEN1
SCHEMBL394379 0.81 TGM2 (0.58) TDP1NAMPTALDH1A1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1048981-B1 Methode for negative type image recording FUJIFILM CORP (JP) 2009-08-19 EP disclosed
EP-1219464-B1 Lithographic printing plate precursor FUJIFILM CORP (JP) 2008-02-13 EP disclosed
US-6890700-B2 Capable of plate-making by scanning exposure based on digital signals, high sensitivity, free of residual color and residual film phenomena, and excellent in resistance to smearing (i.e., staining) and excellent in press life FUJI PHOTO FILM CO., LTD. (JP) 2005-05-10 US disclosed
EP-0854388-B1 Negative-type image recording materials FUJI PHOTO FILM CO LTD (JP) 2003-08-13 EP disclosed
US-20020182538-A1 Capable of plate-making by scanning exposure based on digital signals, high sensitivity, free of residual color and residual film phenomena, and excellent in resistance to smearing (i.e., staining) and excellent in press life FUJIFILM CORPORATION (JP) 2002-12-05 US disclosed
US-6416939-B1 EXPOSURE, HEATING AND DEVELOPMENT FUJI PHOTO FILM CO., LTD. (JP) 2002-07-09 US disclosed
EP-1219464-A2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2002-07-03 EP disclosed
US-6238839-B1 DIMENSIONALLY STABLE METAL SUPPORT COATED WITH A HEAT-INSULATING LAYER, A HYDROPHILIC LAYER AND A THERMOSENSITIVE LIPOPHILIC LAYER; IMAGE QUALITY, MULTICOLOR PRINTS FUJI PHOTO FILM CO., LTD. (JP) 2001-05-29 US disclosed
EP-1048981-A1 Negative type image recording material FUJI PHOTO FILM CO., LTD. (JP) 2000-11-02 EP disclosed
US-6068963-A CONTAINS (A) A POLYMER HAVING A HETEROCYCLIC GROUP CONTAINING AN UNSATURATED BOND THEREIN, (B) A CROSS-LINKING AGENT THAT CROSS-LINKS WITH THE AID OF AN ACID, AND (C) A COMPOUND THAT GENERATES AN ACID UPON EXPOSURE TO LIGHT OR HEAT. FUJI PHOTO FILM CO., LTD. (JP) 2000-05-30 US disclosed
EP-0854388-A2 Negative-type image recording materials FUJI PHOTO FILM CO., LTD. (JP) 1998-07-22 EP disclosed