SCHEMBL382616

SCHEMBL382616

CC(C)(C)[Si](C)(C)OCCCCBr

nearest known ligand 0.38

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DUT P33316 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5651326 0.98 DUT (0.37) DUT
SCHEMBL1535294 0.98 DUT (0.37) DUT
SCHEMBL4778591 0.98 DUT (0.37) DUT
SCHEMBL581065 0.98 DUT (0.37) DUT
SCHEMBL514304 0.98 DUT (0.37) DUT
SCHEMBL5168130 0.98 DUT (0.37) DUT
SCHEMBL741996 0.98 DUT (0.37) DUT
SCHEMBL4773208 0.98 DUT (0.37) DUT
SCHEMBL2805480 0.98 DUT (0.37) DUT
SCHEMBL2285354 0.98 DUT (0.37) DUT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 135 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260137703-A1 2-AMINO-PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE AND 7-AMINO-1-PYRIMIDO[4,5-D]PYRIMIDIN-2(1 H)-ONE DERIVATIVES AS EGFR INHIBITORS FOR THE TREATMENT OF CANCER CANCER RESEARCH TECH LIMITED (GB) 2026-05-21 US disclosed
WO-2026107227-A1 COMPOSITIONS COMPRISING USP1 INHIBITORS AND METHODS OF USING THE SAME EIKON THERAPEUTICS, INC. (US) 2026-05-21 WO disclosed
US-20260102501-A1 ANTI-CANCER NUCLEAR HORMONE RECEPTOR-TARGETING COMPOUNDS NUVATION BIO INC (US) 2026-04-16 US disclosed
US-12590108-B2 Boracic acid compound PHAENO THERAPEUTICS CO., LTD (CN) 2026-03-31 US disclosed
EP-4695241-A1 THIADIAZOLONE DERIVATIVES, COMPOSITIONS AND USES THEREOF Danatlas Pharmaceuticals Co., Ltd. (CN) 2026-02-18 EP disclosed
US-20260034113-A1 THIADIAZOLONE DERIVATIVES, COMPOSITIONS AND USES THEREOF DANATLAS PHARMACEUTICALS CO LTD (CN) 2026-02-05 US disclosed
US-20250367129-A1 Lipid Compounds and Uses Thereof PFIZER (US) 2025-12-04 US disclosed
US-12479838-B2 D3 receptor agonist compounds; methods of preparation; intermediates thereof; and methods of use thereof THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2025-11-25 US disclosed
US-20250353864-A1 INDAZOLE CONTAINING MACROCYCLES AND THEIR USE BLOSSOMHILL THERAPEUTICS INC (US) 2025-11-20 US disclosed
US-12448368-B2 Indole compounds as androgen receptor modulators NIDO BIOSCIENCES, INC. (US) 2025-10-21 US disclosed
US-20050186580-A1 Quality control method for array manufacture AGILENT TECHNOLOGIES, INC. 2005-08-25 US disclosed
US-20050186579-A1 MALDI-MS analysis of nucleic acids bound to a surface AGILENT TECHNOLOGIES, INC. 2005-08-25 US disclosed
US-20050048601-A1 Method for polynucleotide synthesis REGENTS OF THE UNIVERSITY OF COLORADO, THE 2005-03-03 US disclosed
US-20050048496-A1 Method of polynucleotide synthesis using modified support AGILENT TECHNOLOGIES, INC. 2005-03-03 US disclosed
US-20050048497-A1 Cleavable linker for polynucleotide synthesis THE REGENTS OF THE UNIVERSITY OF COLORADO 2005-03-03 US disclosed
EP-1510522-A1 Method of polynucleotide synthesis using modified support Agilent Technologies Inc (US) 2005-03-02 EP disclosed
US-6710048-B2 SELECTIVE INHIBITORS OF VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR TYROSINE KINASE; TO TREAT SOLID-TUMOR CANCERS, ANGIOGENESIS, DIABETIC RETINOPATHY, RHEUMATOID ARTHRITIS, ENDOMETRIOSIS AND PSORIASIS ORTHO-MCNEIL PHARMACEUTICAL, INC. 2004-03-23 US disclosed
EP-1330452-A2 PYRAZINE DERIVATIVES AS MODULATORS OF TYROSINE KINASES Ortho-McNeil Pharmaceutical, Inc. (US) 2003-07-30 EP disclosed
US-20030060629-A1 Pyrazine derivatives as modulators of tyrosine kinases ORTHO-MCNEIL PHARMACEUTICAL, INC. 2003-03-27 US disclosed
WO-2002024681-A2 PYRAZINE DERIVATIVES AS MODULATORS OF TYROSINE KINASES ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) 2002-03-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260137703-A1 2-AMINO-PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE AND 7-AMINO-1-PYRIMIDO[4,5-D]PYRIMIDIN-2(1 H)-ONE DERIVATIVES AS EGFR INHIBITORS FOR THE TREATMENT OF CANCER EGFR, KRAS, O60361 DUT 1465/4885
US-20050048496-A1 Method of polynucleotide synthesis using modified support POLN, POLRMT, POLM DUT 30/4885
US-20260102501-A1 ANTI-CANCER NUCLEAR HORMONE RECEPTOR-TARGETING COMPOUNDS NR5A1, NR5A2, NR3C1 DUT 718/4885
US-12479838-B2 D3 receptor agonist compounds; methods of preparation; intermediates thereof; and methods of use thereof DRD3, ADRB3, VDR DUT 1979/4885
US-20050048601-A1 Method for polynucleotide synthesis POLN, RNGTT, NSUN2 DUT 29/4885
US-20250353864-A1 INDAZOLE CONTAINING MACROCYCLES AND THEIR USE AADAC, PAICS, CYP3A43 DUT 167/4885
US-12590108-B2 Boracic acid compound ME1, GPBAR1, BCL6 DUT 3797/4885
US-20260034113-A1 THIADIAZOLONE DERIVATIVES, COMPOSITIONS AND USES THEREOF SRD5A2, NR3C2, SRD5A1 DUT 736/4885
US-12448368-B2 Indole compounds as androgen receptor modulators AR, FSHR, ADRB3 DUT 1822/4885
US-20050048497-A1 Cleavable linker for polynucleotide synthesis TYMP, POLN, CPSF1 DUT 11/4885
US-20030060629-A1 Pyrazine derivatives as modulators of tyrosine kinases FLT1, FLT4, KDR DUT 3589/4885
US-20250367129-A1 Lipid Compounds and Uses Thereof POLN, PHOSPHO1, NPC1 DUT 1105/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.