Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17146938 | 0.81 | ACHE (0.44) | KMT2ANPC1RAB9AACHETAAR1 | |
| SCHEMBL4391221 | 0.81 | ALDH1A1 (0.67) | KMT2ANPC1RAB9AALDH1A1TSHR | |
| SCHEMBL12774528 | 0.79 | ABCG2 (0.54) | KMT2ANPC1RAB9AACHETAAR1 | |
| SCHEMBL8979321 | 0.78 | ACHE (0.41) | KMT2ANPC1RAB9AALDH1A1ACHE | |
| SCHEMBL9809614 | 0.78 | HTR7 (0.44) | KMT2ANPC1RAB9AALDH1A1TSHR | |
| SCHEMBL27877638 | 0.78 | ACHE (0.41) | KMT2ANPC1RAB9AACHETAAR1 | |
| SCHEMBL19009078 | 0.78 | TAAR1 (0.44) | KMT2ANPC1RAB9AALDH1A1ACHE | |
| SCHEMBL10294031 | 0.78 | ABCG2 (0.42) | KMT2ANPC1RAB9AACHETAAR1 | |
| SCHEMBL8765447 | 0.77 | ACHE (0.44) | KMT2ANPC1RAB9AACHETAAR1 | |
| SCHEMBL3425607 | 0.76 | ALDH1A1 (0.61) | KMT2ANPC1RAB9AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5030537-A | Photoconductive unsymmetrical squaraine compositions | XEROX CORPORATION (US) | 1991-07-09 | — | — | US | claimed |
| US-4967002-A | AROMATIC AMINE AND SQUARIC ACID OR DERIVATIVE, ALIPHATIC ALCOHOL SOLVENT, TRIALKYL ORTHOFORMATE DRYING AGENT | XEROX CORPORATION (US) | 1990-10-30 | — | — | US | claimed |
| US-4607124-A | REACTING SQUARIC ACID, AROMATIC AMINE AND A FLUOROANILINE IN PRESENCE OF ALIPHATIC ALCOHOL | XEROX CORPORATION (US) | 1986-08-19 | — | — | US | claimed |
| US-4585895-A | Processes for the preparation of mixed squaraine compositions | XEROX CORPORATION (US) | 1986-04-29 | — | — | US | claimed |
| US-4525592-A | Process for squaraine compositions | XEROX CORPORATION (US) | 1985-06-25 | — | — | US | claimed |
| US-4524219-A | REACTING AN ALKYL AQUARATE WITH AN N,N-DIALKYLANILINE IN THE PRESENCE OF AN ALKANOL | XEROX CORPORATION (US) | 1985-06-18 | — | — | US | claimed |
| WO-2024130344-A1 | TRANSIENT RECEPTOR POTENTIAL VANILLOID 6 INHIBITORS | UNIQUEST PTY LIMITED (AU) | 2024-06-27 | — | — | WO | disclosed |
| WO-2023239906-A2 | SIALIC ACID DERIVATIVES AND METHODS OF USING SAME | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2023-12-14 | — | — | WO | disclosed |
| EP-3842433-B1 | PYRIDONE-PYRIMIDINE DERIVATIVE ACTING AS KRASG12C MUTEIN INHIBITOR | MEDSHINE DISCOVERY INC (CN) | 2023-11-01 | — | — | EP | disclosed |
| EP-3741756-B1 | PYRIDONE-PYRIMIDINE DERIVATIVE ACTING AS KRASG12C MUTEIN INHIBITOR | MEDSHINE DISCOVERY INC (CN) | 2023-11-01 | — | — | EP | disclosed |
| US-20230339902-A1 | TRICYCLIC LIGANDS FOR DEGRADATION OF IKZF2 OR IKZF4 | C4 THERAPEUTICS, INC. (US) | 2023-10-26 | — | — | US | disclosed |
| US-11753363-B2 | 13-oxidized ingenol derivative and use thereof | TIANJIN PHARMACEUTICAL DA REN TANG GROUP CORP., LTD. TRADITIONAL CHINESE MEDICINE RESEARCH INSTITUTE (CN) | 2023-09-12 | — | — | US | disclosed |
| CN-113880750-B | Synthesis method of chiral 3-substituted-3-aryl oxindole compound | 上海交通大学 | 2023-02-10 | — | — | CN | disclosed |
| EP-0145400-A2 | Photoconductive devices containing novel squaraine compounds | XEROX CORPORATION (US) | 1985-06-19 | — | — | EP | disclosed |
| US-4524219-A | REACTING AN ALKYL AQUARATE WITH AN N,N-DIALKYLANILINE IN THE PRESENCE OF AN ALKANOL | XEROX CORPORATION (US) | 1985-06-18 | — | — | US | disclosed |
| US-4524220-A | REACTING SQUARIC ACID AND AN AROMATIC DIAMINE; PHOTOSTABILITY | XEROX CORPORATION (US) | 1985-06-18 | — | — | US | disclosed |
| EP-0144206-A2 | Process for synthesising squaraine compositions | XEROX CORPORATION (US) | 1985-06-12 | — | — | EP | disclosed |
| US-4523035-A | BLUE AND GREEN PIGMENTS | XEROX CORPORATION (US) | 1985-06-11 | — | — | US | disclosed |
| US-4521621-A | Novel squarine systems | XEROX CORPORATION (US) | 1985-06-04 | — | — | US | disclosed |
| US-4486520-A | Photoconductive devices containing novel squaraine compositions | XEROX CORPORATION (US) | 1984-12-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230339902-A1 | TRICYCLIC LIGANDS FOR DEGRADATION OF IKZF2 OR IKZF4 | IKZF1, IKZF3, IKZF2 | KMT2A 869/4885NPC1 1565/4885RAB9A 4579/4885 |
| US-11753363-B2 | 13-oxidized ingenol derivative and use thereof | MMP8, CXCL8, PMAIP1 | KMT2A 4663/4885NPC1 2747/4885RAB9A 1364/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.