Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 4/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.41 |
| ▸ | CHRNA10 | Q9GZZ6 | 3/20 | 0.41 |
| ▸ | CHRNA9 | Q9UGM1 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | DRD4 | P21917 | 2/20 | 0.32 |
| ▸ | DRD3 | P35462 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3520804 | 0.99 | CHRNB2 (0.43) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| Hydrochloric Acid SCHEMBL3853489 | 0.98 | CHRNB2 (0.40) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| SCHEMBL18560589 | 0.97 | CHRNB2 (0.41) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| Hydrochloric Acid SCHEMBL1152121 | 0.96 | CHRNB2 (0.41) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| SCHEMBL3837846 | 0.91 | CHRNB2 (0.44) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| Hydrochloric Acid SCHEMBL3849824 | 0.89 | CHRNB2 (0.42) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| SCHEMBL13646840 | 0.82 | HTT (0.41) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| SCHEMBL13714359 | 0.81 | CHRNB2 (0.38) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| SCHEMBL16078200 | 0.80 | EGFR (0.40) | HTTEGFRKDM4EDRD2DRD4 | |
| SCHEMBL3841138 | 0.78 | VCP (0.32) | EGFRDRD2DRD4DRD3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2464424-B1 | DYE COMPOSITION COMPRISING A HETEROCYCLIC OXIDATION BASE AND AN INDOLE COUPLER | OREAL (FR) | 2019-09-25 | — | — | EP | claimed |
| EP-2651516-B1 | DYE COMPOSITION COMPRISING A HETEROCYCLIC OXIDATION BASE AND A 4-AMINOINDOLE COUPLER | L'ORÉAL (FR) | 2017-06-14 | — | — | EP | claimed |
| EP-2155153-B1 | DYEING COMPOSITION COMPRISING A SPECIFIC AMINOPYRAZOLOPYRIDINE OXIDATION BASE, A COUPLER AND A SPECIFIC SURFACTANT | L'ORÉAL (FR) | 2017-03-01 | — | — | EP | claimed |
| EP-2651935-B1 | DYEING COMPOSITION COMPRISING A FATTY SUBSTANCE, A PYRAZOLOPYRIDINE OXIDATION BASE AND A COUPLER | ORÉAL L (FR) | 2016-11-23 | — | — | EP | claimed |
| EP-1792903-B1 | Composition for the dyeing of keratin fibres comprising at least one cationic 3-amino-pyrazolopyridine derivative | OREAL (FR) | 2009-10-14 | — | — | EP | claimed |
| WO-2008149005-A2 | DYE COMPOSITION COMPRISING AN AMINOPYRAZOLOPYRIDINE OXIDATION BASE AND A SOURCE OF CARBONATE IONS | L'OREAL (FR) | 2008-12-11 | — | — | WO | claimed |
| EP-1992331-A1 | Dyeing composition comprising an aminopyrazolopyridine oxidation base, a coupler and a specific polyol | L'Oreal (FR) | 2008-11-19 | — | — | EP | claimed |
| EP-1992330-A2 | Process for colouring keratinous fibres comprising the application of an aminopyrazolopyridine oxidation base in the absence of oxidizing agent | L'Oreal (FR) | 2008-11-19 | — | — | EP | claimed |
| EP-1992329-A1 | Dyeing composition comprising an aminopyrazolopyridine oxidation base and a specific associative polymer | L'Oréal (FR) | 2008-11-19 | — | — | EP | claimed |
| US-11730688-B2 | Composition for dyeing the hair, comprising a heterocyclic oxidation base and a 2-amino-5-ethylphenol coupler | L'OREAL (FR) | 2023-08-22 | — | — | US | disclosed |
| US-10568821-B2 | Dye composition comprising a para-phenylenediamine oxidation base and a heterocyclic oxidation base | L'OREAL (FR) | 2020-02-25 | — | — | US | disclosed |
| EP-2464424-B1 | DYE COMPOSITION COMPRISING A HETEROCYCLIC OXIDATION BASE AND AN INDOLE COUPLER | OREAL (FR) | 2019-09-25 | — | — | EP | disclosed |
| US-20170354580-A1 | DYE COMPOSITION COMPRISING A PARA-PHENYLENEDIAMINE OXIDATION BASE AND A HETEROCYCLIC OXIDATION BASE | L'OREAL (FR) | 2017-12-14 | — | — | US | disclosed |
| EP-2651516-B1 | DYE COMPOSITION COMPRISING A HETEROCYCLIC OXIDATION BASE AND A 4-AMINOINDOLE COUPLER | L'ORÉAL (FR) | 2017-06-14 | — | — | EP | disclosed |
| EP-1992331-A1 | Dyeing composition comprising an aminopyrazolopyridine oxidation base, a coupler and a specific polyol | L'Oreal (FR) | 2008-11-19 | — | — | EP | disclosed |
| EP-1992331-A1 | Dyeing composition comprising an aminopyrazolopyridine oxidation base, a coupler and a specific polyol | L'Oreal (FR) | 2008-11-19 | — | — | EP | disclosed |
| EP-1992330-A2 | Process for colouring keratinous fibres comprising the application of an aminopyrazolopyridine oxidation base in the absence of oxidizing agent | L'Oreal (FR) | 2008-11-19 | — | — | EP | disclosed |
| US-20070136959-A1 | Composition for dyeing keratin fibers comprising at least one cationic 3-amino-pyrazolopyridine derivative, and methods of use thereof | L'OREAL S.A. (FR) | 2007-06-21 | — | — | US | disclosed |
| EP-1792903-A1 | Composition for the dyeing of keratin fibres comprising at least one cationic 3-amino-pyrazolopyridine derivative | L'OREAL (FR) | 2007-06-06 | — | — | EP | disclosed |
| EP-1792903-A1 | Composition for the dyeing of keratin fibres comprising at least one cationic 3-amino-pyrazolopyridine derivative | L'OREAL (FR) | 2007-06-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10568821-B2 | Dye composition comprising a para-phenylenediamine oxidation base and a heterocyclic oxidation base | KRT18, DSG1, SQOR | CHRNB2 1274/4885CHRNB4 1039/4885CHRNA3 2424/4885 |
| US-20070136959-A1 | Composition for dyeing keratin fibers comprising at least one cationic 3-amino-pyrazolopyridine derivative, and methods of use thereof | KRT18, COX5A, PNPO | CHRNB2 1840/4885CHRNB4 1294/4885CHRNA3 1885/4885 |
| US-11730688-B2 | Composition for dyeing the hair, comprising a heterocyclic oxidation base and a 2-amino-5-ethylphenol coupler | KRT18, COX5B, COX5A | CHRNB2 1111/4885CHRNB4 1251/4885CHRNA3 2063/4885 |
| US-20170354580-A1 | DYE COMPOSITION COMPRISING A PARA-PHENYLENEDIAMINE OXIDATION BASE AND A HETEROCYCLIC OXIDATION BASE | KRT18, DSG1, SQOR | CHRNB2 1274/4885CHRNB4 1039/4885CHRNA3 2424/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.