SCHEMBL383913

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2087952	0.75	CETP (0.67)	MAPTALDH1A1KDM4ELMNATSHR
	SCHEMBL10168172	0.73	MAPT (0.59)	HTTMAPTALDH1A1KDM4EHSD17B10
	SCHEMBL9352178	0.72	HTT (1.00)	HTTMAPTALDH1A1KDM4EHSD17B10
	SCHEMBL16376471	0.72	GPR3 (0.62)	HTTMAPTALDH1A1KDM4EHSD17B10
	SCHEMBL12284944	0.70	CETP (0.59)	ALDH1A1KDM4ELMNATSHRCETP
	SCHEMBL27653133	0.70	MAPT (0.61)	HTTMAPTALDH1A1KDM4EHSD17B10
	Adosopine SCHEMBL2109279	0.69	MAPT (0.50)	HTTMAPTALDH1A1KDM4EHSD17B10
	SCHEMBL10812522	0.69	RXFP1 (0.52)	HTTMAPTALDH1A1KDM4ELMNA
	SCHEMBL4728699	0.69	NPY5R (0.78)	MAPTKDM4ELMNAMEN1KMT2A
	SCHEMBL5706504	0.68	CETP (0.71)	ALDH1A1KDM4ELMNATSHRCETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.