Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | PDK1 | Q15118 | 3/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.43 |
| ▸ | PDK3 | Q15120 | 3/20 | 0.43 |
| ▸ | PDK4 | Q16654 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29469256 | 1.00 | CETP (0.59) | CETPL3MBTL1KDM4ELMNAALOX12 | |
| SCHEMBL3787214 | 0.84 | CETP (0.50) | CETPL3MBTL1KDM4ELMNAALOX12 | |
| SCHEMBL5706504 | 0.84 | CETP (0.71) | CETPL3MBTL1KDM4ELMNAALOX12 | |
| SCHEMBL6517475 | 0.84 | JAK2 (0.49) | L3MBTL1PDK1PDK2PDK3PDK4 | |
| SCHEMBL29955558 | 0.84 | JAK2 (0.49) | L3MBTL1PDK1PDK2PDK3PDK4 | |
| SCHEMBL3788778 | 0.81 | CETP (0.54) | CETPL3MBTL1KDM4ELMNAALOX12 | |
| SCHEMBL2087952 | 0.80 | CETP (0.67) | CETPL3MBTL1KDM4ELMNAALOX12 | |
| SCHEMBL2952211 | 0.80 | CETP (0.49) | CETPL3MBTL1KDM4ELMNAALOX12 | |
| SCHEMBL56441 | 0.79 | GAA (0.50) | KDM4ELMNARAB9AALDH1A1MAPT | |
| SCHEMBL3149525 | 0.79 | RAB9A (0.45) | KDM4ERAB9AALDH1A1POLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1696912-B1 | PYRAZOLOPYRIDINES AND ANALOGS THEREOF | 3M INNOVATIVE PROPERTIES CO (US) | 2016-05-11 | — | — | EP | disclosed |
| US-9145410-B2 | Pyrazolopyridines and analogs thereof | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2015-09-29 | — | — | US | disclosed |
| US-9145410-B2 | Pyrazolopyridines and analogs thereof | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2015-09-29 | — | — | US | disclosed |
| US-20150157783-A1 | METHOD TO SELECTIVELY BIND AND EXTRACT PHOSPHATE | NATIONAL SCIENCE FOUNDATION | 2015-06-11 | — | — | US | disclosed |
| US-20150157783-A1 | METHOD TO SELECTIVELY BIND AND EXTRACT PHOSPHATE | NATIONAL SCIENCE FOUNDATION | 2015-06-11 | — | — | US | disclosed |
| US-20150157783-A1 | METHOD TO SELECTIVELY BIND AND EXTRACT PHOSPHATE | NATIONAL SCIENCE FOUNDATION | 2015-06-11 | — | — | US | disclosed |
| US-9012651-B2 | TRPV3 modulators | ABBVIE INC. (US) | 2015-04-21 | — | — | US | disclosed |
| EP-2376491-B1 | PYRROLOTRIAZINES AS ALK AND JAK2 INHIBITORS | CEPHALON INC (US) | 2015-03-04 | — | — | EP | disclosed |
| US-8471005-B2 | Pyrrolotriazines as ALK and JAK2 inhibitors | CEPHALON, INC. (US) | 2013-06-25 | — | — | US | disclosed |
| US-8394803-B2 | Gyrase inhibitors and uses thereof | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2013-03-12 | — | — | US | disclosed |
| WO-2005079195-A2 | PYRAZOLOPYRIDINES AND ANALOGS THEREOF | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2005-09-01 | — | — | WO | disclosed |
| EP-1054869-B1 | 3,4-DIHYDROQUINOLINE DERIVATIVES AS NITROGEN MONOXIDE SYNTHASE (NOS) INHIBITORS | SCHERING AG (DE) | 2004-09-22 | — | — | EP | disclosed |
| US-20040063739-A1 | N8, n13 -disubstituted quino[4,3,2-kl]acridinium salts as therapeutic agents | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2004-04-01 | — | — | US | disclosed |
| EP-1330456-A2 | N8,N13 -DISUBSTITUTED QUINO 4,3,2-KL]ACRIDINIUM SALTS AS THERAPEUTIC AGENTS | Cancer Research Technology Limited (GB) | 2003-07-30 | — | — | EP | disclosed |
| WO-2002030932-A2 | N8,N13-DISUBSTITUTED QUINO[4,3,2-KL]ACRIDINIUM SALTS AS THERAPEUTIC AGENTS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2002-04-18 | — | — | WO | disclosed |
| EP-1054869-A1 | 3,4-DIHYDROQUINOLINE DERIVATIVES AS NITROGEN MONOXIDE SYNTHASE (NOS) INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 2000-11-29 | — | — | EP | disclosed |
| WO-1999041240-A1 | 3,4-DIHYDROQUINOLINE DERIVATIVES AS NITROGEN MONOXIDE SYNTHASE (NOS) INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 1999-08-19 | — | — | WO | disclosed |
| EP-0619804-B1 | HERBICIDAL ACYLATED AMINO-(PHENYL- OR PYRIDINYL- OR THIENYL-)-PHENYL DERIVATIVES | DU PONT (US) | 1996-05-22 | — | — | EP | disclosed |
| EP-0619804-A1 | HERBICIDAL ACYLATED AMINO-(PHENYL- OR PYRIDINYL- OR THIENYL-)-PHENYL DERIVATIVES. | DU PONT (US) | 1994-10-19 | — | — | EP | disclosed |
| WO-1993011097-A1 | HERBICIDAL ACYLATED AMINO-(PHENYL- OR PYRIDINYL- OR THIENYL-)-PHENYL DERIVATIVES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-06-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063739-A1 | N8, n13 -disubstituted quino[4,3,2-kl]acridinium salts as therapeutic agents | TERT, MKI67, NQO2 | CETP 3226/4885L3MBTL1 1663/4885KDM4E 322/4885 |
| US-20150157783-A1 | METHOD TO SELECTIVELY BIND AND EXTRACT PHOSPHATE | PPA1, SLC34A3, SLC34A2 | CETP 1797/4885L3MBTL1 4652/4885KDM4E 751/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.