Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.41 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13790221 | 0.87 | CYP2D6 (0.50) | KDM4ECYP2D6PIM1PIM2GRIK1 | |
| SCHEMBL1047423 | 0.83 | PIM1 (0.46) | KDM4ETSHRALDH1A1LMNATP53 | |
| SCHEMBL9060861 | 0.82 | NFE2L2 (0.62) | KDM4ETSHRALDH1A1LMNATP53 | |
| SCHEMBL9061558 | 0.82 | RELA (0.59) | CYP2D6PIM1PIM2NFE2L2 | |
| SCHEMBL9061561 | 0.82 | RELA (0.59) | CYP2D6PIM1PIM2NFE2L2 | |
| SCHEMBL9060858 | 0.82 | NFE2L2 (0.62) | KDM4ETSHRALDH1A1LMNATP53 | |
| SCHEMBL7606991 | 0.81 | LMNA (0.59) | KDM4ETSHRALDH1A1LMNATP53 | |
| SCHEMBL13990592 | 0.80 | CYP2D6 (0.43) | KDM4EALDH1A1CYP2D6PIM1PIM2 | |
| SCHEMBL8428819 | 0.80 | CYP2D6 (0.43) | KDM4ETSHRALDH1A1LMNATP53 | |
| SCHEMBL8428816 | 0.80 | CYP2D6 (0.43) | KDM4ETSHRALDH1A1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2822938-B1 | RODENTICIDAL NORBORMIDE ANALOGUES | LANDCARE RES NEW ZEALAND LIMITED (NZ) | 2019-07-03 | — | — | EP | disclosed |
| WO-2018068666-A1 | MICROTUBULE PROTEIN INHIBITOR | 深圳海王医药科技研究院有限公司 | 2018-04-19 | — | — | WO | disclosed |
| US-9198420-B2 | Rodenticidal norbormide analogues | LANDCARE RESEARCH NEW ZEALAND LIMITED (NZ) | 2015-12-01 | — | — | US | disclosed |
| US-20150025113-A1 | RODENTICIDAL NORBORMIDE ANALOGUES | ANIMAL CONTROL PRODUCTS LIMITED (NZ) | 2015-01-22 | — | — | US | disclosed |
| CN-101370810-B | Diaza-spiro [4.5] decanes useful as pesticides | SYNGENTA PARTICIPATIONS AG (CH) | 2013-01-02 | — | — | CN | disclosed |
| EP-1613639-B1 | AVERMECTINS SUBSTITUTED IN THE 4'' AND 4´-POSITIONS HAVING PESTICIDAL PROPERTIES | MERIAL LTD (US) | 2010-10-06 | — | — | EP | disclosed |
| EP-1979354-B1 | DIAZA-SPIRO-[4, 5]-DECANES USEFUL AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-11-11 | — | — | EP | disclosed |
| US-7326727-B2 | Furanthiazole derivatives as heparanase inhibitors | OXFORD GLYCOSCIENCES (UK) LTD. (GB) | 2008-02-05 | — | — | US | disclosed |
| US-7326727-B2 | Furanthiazole derivatives as heparanase inhibitors | OXFORD GLYCOSCIENCES (UK) LTD. (GB) | 2008-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150025113-A1 | RODENTICIDAL NORBORMIDE ANALOGUES | CASP7, RANBP1, CASP3 | KDM4E 2937/4885TSHR 3163/4885ALDH1A1 1772/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.