Methacrylic Acid

Methacrylic Acid

SCHEMBL3845692

C=C(C)C(=O)O.O=C(/C=C\C(=O)OC(=O)C1CC2C=CC1C2)OC(=O)C1CC2C=CC1C2

nearest known ligand 0.40

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.40
LMNA P02545 1/20 0.40
ALDH1A1 P00352 7/20 0.39
KMT2A Q03164 3/20 0.36
HPGD P15428 1/20 0.35
POLB P06746 2/20 0.34
RAB9A P51151 1/20 0.34
HSD17B10 Q99714 2/20 0.33
APEX1 P27695 1/20 0.33
RECQL P46063 1/20 0.33
BLM P54132 1/20 0.33
ESR2 Q92731 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
MEN1 O00255 1/20 0.31
ALOX15 P16050 1/20 0.31
TSHR P16473 1/20 0.31
HTT P42858 1/20 0.31
THRB P10828 1/20 0.31
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6318871 0.88 KDM4E (0.49) KDM4ELMNAALDH1A1KMT2AHPGD
Acrylic Acid SCHEMBL3841669 0.86 KDM4E (0.41) KDM4ELMNAALDH1A1KMT2AHPGD
SCHEMBL7891625 0.77 LMNA (0.50) KDM4ELMNAALDH1A1KMT2AHPGD
SCHEMBL14378676 0.77 LMNA (0.57) KDM4ELMNAALDH1A1KMT2AHPGD
SCHEMBL2776167 0.77 LMNA (0.57) KDM4ELMNAALDH1A1KMT2AHPGD
SCHEMBL28171681 0.72 HSD11B1 (0.43) KDM4ELMNAALDH1A1KMT2AHPGD
Methacrylic Acid SCHEMBL28887221 0.71 KDM4E (0.38) KDM4ELMNAALDH1A1POLBAPEX1
Methacrylic Acid SCHEMBL1947733 0.71 KDM4E (0.38) KDM4ELMNAALDH1A1POLBAPEX1
SCHEMBL16766467 0.70 ALDH1A1 (0.43) KDM4ELMNAALDH1A1KMT2AHPGD
SCHEMBL24908346 0.70 KDM4E (0.58) KDM4ELMNAALDH1A1KMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1449833-B1 BISIMIDE COMPOUND, ACID GENERATOR AND RESIST COMPOSITION EACH CONTAINING THE SAME, AND METHOD OF FORMING PATTERN FROM THE COMPOSITION WAKO PURE CHEM IND LTD (JP) 2009-09-09 EP disclosed
US-7374857-B2 Bismide compound, acid generator and resist composition each containing the same, and method of forming pattern from the composition WAKO PURE CHEMICAL INDUSTRIES LTD. (JP) 2008-05-20 US disclosed
US-20050038261-A1 Bismide compound, acid generator and resist composition each containing the same, and method of forming pattern from the composition WAKO PURE CHEMICAL INDUSTRIES LTD. (JP) 2005-02-17 US disclosed
EP-1449833-A1 BISIMIDE COMPOUND, ACID GENERATOR AND RESIST COMPOSITION EACH CONTAINING THE SAME, AND METHOD OF FORMING PATTERN FROM THE COMPOSITION Wako Pure Chemical Industries, Ltd. (JP) 2004-08-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050038261-A1 Bismide compound, acid generator and resist composition each containing the same, and method of forming pattern from the composition ASIC1, GAR1, RER1 KDM4E 2501/4885LMNA 1522/4885ALDH1A1 633/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.