Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | DRD2 | P14416 | 2/20 | 0.53 |
| ▸ | DRD4 | P21917 | 2/20 | 0.53 |
| ▸ | DRD3 | P35462 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 6/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | PRNP | P04156 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2226447 | 0.83 | DRD2 (0.53) | KDM4EDRD2DRD4DRD3HPGD | |
| SCHEMBL2097145 | 0.80 | KDM4E (0.58) | KDM4EDRD2DRD4DRD3HPGD | |
| SCHEMBL5546130 | 0.79 | RAB9A (0.56) | KDM4EDRD2DRD4DRD3HPGD | |
| SCHEMBL14736420 | 0.77 | LMNA (0.56) | KDM4EDRD2DRD4DRD3HPGD | |
| SCHEMBL118764 | 0.77 | GFER (0.71) | KDM4EDRD2DRD4DRD3HPGD | |
| SCHEMBL104951 | 0.77 | KDM4E (0.58) | KDM4EDRD2DRD4DRD3HPGD | |
| SCHEMBL3368273 | 0.77 | DRD2 (0.57) | KDM4EDRD2DRD4DRD3HPGD | |
| SCHEMBL2094508 | 0.77 | DRD2 (0.57) | KDM4EDRD2DRD4DRD3HPGD | |
| SCHEMBL10031024 | 0.77 | LMNA (0.59) | KDM4EDRD2DRD4DRD3HPGD | |
| SCHEMBL104385 | 0.77 | DRD2 (0.57) | KDM4EDRD2DRD4DRD3HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190071407-A1 | ISOXAZOLINE DERIVATIVES AS INSECTICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2019-03-07 | — | — | US | disclosed |
| EP-2536698-B1 | ISOXAZOLINE DERIVATIVES AS INSECTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2015-06-10 | — | — | EP | disclosed |
| CN-101370810-B | Diaza-spiro [4.5] decanes useful as pesticides | SYNGENTA PARTICIPATIONS AG (CH) | 2013-01-02 | — | — | CN | disclosed |
| EP-1979354-B1 | DIAZA-SPIRO-[4, 5]-DECANES USEFUL AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-11-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190071407-A1 | ISOXAZOLINE DERIVATIVES AS INSECTICIDES | ACHE, CHRM1, ITPR3 | KDM4E 3040/4885DRD2 2484/4885DRD4 1681/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.