SCHEMBL3848645

SCHEMBL3848645

CC[Si](CC)(CC)OC(=O)c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.53
TSHR P16473 4/20 0.52
F2 P00734 1/20 0.50
ALDH1A1 P00352 4/20 0.48
TDP1 Q9NUW8 3/20 0.47
MAPK1 P28482 1/20 0.46
HIF1A Q16665 1/20 0.46
SLC6A2 P23975 1/20 0.46
SLC6A3 Q01959 1/20 0.46
KMT2A Q03164 1/20 0.46
HSD17B10 Q99714 1/20 0.44
CES2 O00748 1/20 0.44
CES1 P23141 1/20 0.44
GAA P10253 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
KDM4E B2RXH2 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.42
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
CYP1A2 P05177 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL201962 0.84 LMNA (0.53) LMNATSHRF2ALDH1A1TDP1
SCHEMBL202539 0.82 LMNA (0.52) LMNATSHRF2ALDH1A1TDP1
SCHEMBL3973273 0.78 LMNA (0.47) LMNATSHRF2ALDH1A1TDP1
SCHEMBL20819062 0.77 LMNA (0.50) LMNATSHRF2ALDH1A1TDP1
SCHEMBL203317 0.77 TSHR (0.58) LMNATSHRF2ALDH1A1TDP1
SCHEMBL7070049 0.77 TSHR (0.58) LMNATSHRF2ALDH1A1TDP1
SCHEMBL1759366 0.77 TSHR (0.58) LMNATSHRF2ALDH1A1TDP1
SCHEMBL10912072 0.77 LMNA (0.46) LMNATSHRF2ALDH1A1TDP1
SCHEMBL10733991 0.76 LMNA (0.61) LMNATSHRF2ALDH1A1TDP1
SCHEMBL9038964 0.76 ALDH1A1 (0.40) LMNATSHRALDH1A1MAPK1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116410357-A Multi-element external electron donor composition and application thereof 中国石油天然气股份有限公司 2023-07-11 CN claimed
US-12434998-B2 Resin-coated ultra-thin glass TORAY INDUSTRIES, INC. (JP) 2025-10-07 US disclosed
US-11912731-B2 Use of silylated formiates as hydrosilane equivalents COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2024-02-27 US disclosed
US-20230365458-A1 RESIN-COATED ULTRA-THIN GLASS TORAY INDUSTRIES, INC. (JP) 2023-11-16 US disclosed
CN-110573964-B Negative photosensitive resin composition and cured film 东丽株式会社 2023-11-03 CN disclosed
CN-116410357-A Multi-element external electron donor composition and application thereof 中国石油天然气股份有限公司 2023-07-11 CN disclosed
CN-101226329-B Radiation sensitive resin composition, laminated insulating film, micro lens and preparation method thereof JSR CORP 2012-09-05 CN disclosed
CN-100554315-C Organopolysiloxane and contain the solidification compound of organopolysiloxane TOAGOSEI CO LTD (JP) 2009-10-28 CN disclosed
US-7576142-B2 Polyorganosiloxane and curable composition containing same TOAGOSEI CO., LTD. (JP) 2009-08-18 US disclosed
EP-1775317-B1 POLYORGANOSILOXANE AND CURABLE COMPOSITION CONTAINING SAME TOAGOSEI CO LTD (JP) 2009-04-15 EP disclosed
US-20080033137-A1 Polyorganosiloxane And Curable Composition Containing Same TOAGOSEI CO., LTD. (JP) 2008-02-07 US disclosed
CN-1965016-A Polyorganosiloxane and curable composition containing same TOAGOSEI CO LTD (JP) 2007-05-16 CN disclosed
EP-1775317-A1 POLYORGANOSILOXANE AND CURABLE COMPOSITION CONTAINING SAME TOAGOSEI CO., LTD. (JP) 2007-04-18 EP disclosed
US-20070055034-A1 Process for producing cation-curable silicon compound TOAGOSEI CO., LTD. (JP) 2007-03-08 US disclosed
CN-1753936-A Process for producing cation-curable silicon compound TOAGOSEI CO LTD (JP) 2006-03-29 CN disclosed
EP-1598389-A1 PROCESS FOR PRODUCING CATION-CURABLE SILICON COMPOUND TOAGOSEI CO., LTD. (JP) 2005-11-23 EP disclosed
EP-0564004-B1 A highly stereoregular polypropylene CHISSO CORP (JP) 1996-09-25 EP disclosed
EP-0564004-A1 A highly stereoregular polypropylene CHISSO CORPORATION (JP) 1993-10-06 EP disclosed
US-5077341-A Using coordination catalyst CHISSO CORPORATION (JP) 1991-12-31 US disclosed
EP-0404519-A2 A process for producing a high-stiffness polypropylene CHISSO CORPORATION (JP) 1990-12-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11912731-B2 Use of silylated formiates as hydrosilane equivalents PFAS, EPM2A, CYP2F1 LMNA 400/4885TSHR 3111/4885F2 7/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.