Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 9/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | PREP | P48147 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.38 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23458984 | 0.75 | ALDH1A1 (0.42) | ALDH1A1 | |
| SCHEMBL23458987 | 0.75 | ALDH1A1 (0.42) | ALDH1A1 | |
| SCHEMBL28485250 | 0.72 | ALDH1A1 (0.42) | ALDH1A1 | |
| SCHEMBL908981 | 0.67 | SCD5 (0.57) | DPP4ABHD6DAGLA | |
| SCHEMBL23459127 | 0.67 | SCD5 (0.57) | DPP4ABHD6DAGLA | |
| SCHEMBL27168378 | 0.67 | FAAH (0.37) | ALDH1A1ABHD6DAGLATSHR | |
| SCHEMBL27168346 | 0.67 | AOC3 (0.38) | ALDH1A1ABHD6DAGLATSHR | |
| SCHEMBL4964339 | 0.66 | HSD11B1 (0.61) | DPP4ABHD6DAGLA | |
| SCHEMBL4629395 | 0.66 | HSD11B1 (0.61) | DPP4ABHD6DAGLA | |
| SCHEMBL27168362 | 0.65 | FAAH (0.35) | ALDH1A1ABHD6DAGLATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2102180-A1 | SUBSTITUTED AMINOFURANONES AND THEIR USE | Bayer Schering Pharma Aktiengesellschaft (DE) | 2009-09-23 | — | — | EP | disclosed |
| WO-2008071359-A1 | SUBSTITUTED AMINOFURANONES AND THEIR USE | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-06-19 | — | — | WO | disclosed |