Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28017054 | 0.84 | TRPA1 (0.31) | TRPA1 | |
| SCHEMBL28134334 | 0.76 | BACE1 (0.33) | — | |
| SCHEMBL14428150 | 0.72 | HSD17B10 (0.33) | — | |
| SCHEMBL11314135 | 0.72 | TRPA1 (0.36) | TRPA1 | |
| SCHEMBL926937 | 0.70 | HTR5A (0.35) | — | |
| SCHEMBL29639106 | 0.70 | HTR5A (0.35) | — | |
| Hydrochloric Acid SCHEMBL30881482 | 0.68 | HTR5A (0.34) | — | |
| Iodide SCHEMBL29258426 | 0.68 | HTR5A (0.37) | — | |
| SCHEMBL30984323 | 0.68 | AHR (0.36) | — | |
| SCHEMBL15235375 | 0.68 | CYP3A4 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106232600-A | Dihydroindole 2 ketone and 1,3 pyrrolin also [3,2 c] pyridine 2 ketone derivatives | 豪夫迈·罗氏有限公司 | 2016-12-14 | — | — | CN | disclosed |
| US-8287775-B2 | Photochromic material | KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) | 2012-10-16 | — | — | US | disclosed |
| US-8287775-B2 | Photochromic material | KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) | 2012-10-16 | — | — | US | disclosed |
| US-20110198546-A1 | PHOTOCHROMIC MATERIAL | KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) | 2011-08-18 | — | — | US | disclosed |
| US-20110198546-A1 | PHOTOCHROMIC MATERIAL | KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) | 2011-08-18 | — | — | US | disclosed |
| EP-1308480-B1 | CYANINE DYES | FUJIFILM CORP (JP) | 2009-11-11 | — | — | EP | disclosed |
| US-6939975-B2 | Cyanine dyes | FUJI PHOTO FILM CO., LTD. (JP) | 2005-09-06 | — | — | US | disclosed |
| US-20040054192-A1 | Cyanine dyes | FUJIFILM CORPORATION (JP) | 2004-03-18 | — | — | US | disclosed |
| EP-1308480-A1 | CYANINE DYES | FUJI PHOTO FILM CO., LTD. (JP) | 2003-05-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040054192-A1 | Cyanine dyes | IK, PYM1, CLIC1 | TRPA1 3206/4885PDE4B 4876/4885 |
| US-20110198546-A1 | PHOTOCHROMIC MATERIAL | PPOX, RAD51, DCLRE1A | TRPA1 588/4885PDE4B 4107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.