Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3851703 | 0.90 | PLA2G2A (0.39) | PLA2G2A | |
| SCHEMBL3854484 | 0.90 | PLK4 (0.43) | PLA2G2A | |
| SCHEMBL3853002 | 0.89 | NPC1 (0.43) | PLA2G2A | |
| SCHEMBL3857091 | 0.84 | ESR1 (0.48) | — | |
| SCHEMBL3853290 | 0.84 | ESR1 (0.40) | PLA2G2A | |
| SCHEMBL3854513 | 0.83 | PPARG (0.43) | — | |
| SCHEMBL3853281 | 0.80 | PLA2G2A (0.50) | PLA2G2APLA2G1B | |
| SCHEMBL3856500 | 0.80 | ESR1 (0.44) | — | |
| SCHEMBL3853687 | 0.79 | HTR6 (0.45) | — | |
| SCHEMBL3857137 | 0.79 | PLA2G2A (0.61) | PLA2G2APLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582773-B2 | Substituted phenyl indoles | WYETH (US) | 2009-09-01 | — | — | US | claimed |
| US-20050070592-A1 | Substituted phenyl indoles | WYETH (US) | 2005-03-31 | — | — | US | claimed |
| US-7582773-B2 | Substituted phenyl indoles | WYETH (US) | 2009-09-01 | — | — | US | disclosed |
| US-20050070592-A1 | Substituted phenyl indoles | WYETH (US) | 2005-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050070592-A1 | Substituted phenyl indoles | TPH2, IDO2, AANAT | PLA2G2A 3821/4885PLA2G1B 3476/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.