SCHEMBL3851729

SCHEMBL3851729

CC(Cl)C(=O)Oc1coccc1=S

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 1/20 0.38
ADORA2B P29275 3/20 0.34
TRPA1 O75762 1/20 0.33
ALOX5 P09917 2/20 0.33
CYP3A4 P08684 1/20 0.33
SLC1A3 P43003 1/20 0.30
SLC1A2 P43004 1/20 0.30
SLC1A1 P43005 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20363557 0.71 MMP2 (0.42) MMP2ADORA2B
SCHEMBL125575 0.69 ALOX15 (0.41) ADORA2BTRPA1ALOX5CYP3A4SLC1A3
SCHEMBL3676274 0.66 ELANE (0.55)
SCHEMBL27804410 0.65 HPGD (0.44)
SCHEMBL28966310 0.62 ELANE (0.52) TRPA1ALOX5CYP3A4
SCHEMBL11219681 0.62 TSHR (0.41)
SCHEMBL11229156 0.61 ELANE (0.50) ALOX5
SCHEMBL9485663 0.61 ELANE (0.53)
SCHEMBL27601772 0.60 SLC6A3 (0.59)
SCHEMBL126289 0.60 ALOX15 (0.41) TRPA1CYP3A4SLC1A3SLC1A2SLC1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7576213-B2 Vinylogous 4H-pyrones and their use in promoting plant growth THE UNIVERSITY OF WESTERN AUSTRALIA (AU) 2009-08-18 US claimed
US-20070105721-A1 Vinylogous 4-Hpyrones and their use in promoting plant growth THE UNIVERSITY OF WESTERN AUSTRALIA (AU) 2007-05-10 US claimed
WO-2005061515-A1 VINYLOGOUS 4H-PYRONES AND THEIR USE IN PROMOTING PLANT GROWTH BOTANICAL GARDENS AND PARKS AUTHORITY (AU) 2005-07-07 WO claimed
US-7576213-B2 Vinylogous 4H-pyrones and their use in promoting plant growth THE UNIVERSITY OF WESTERN AUSTRALIA (AU) 2009-08-18 US disclosed
US-7576213-B2 Vinylogous 4H-pyrones and their use in promoting plant growth THE UNIVERSITY OF WESTERN AUSTRALIA (AU) 2009-08-18 US disclosed
US-7576213-B2 Vinylogous 4H-pyrones and their use in promoting plant growth THE UNIVERSITY OF WESTERN AUSTRALIA (AU) 2009-08-18 US disclosed
US-20070105721-A1 Vinylogous 4-Hpyrones and their use in promoting plant growth THE UNIVERSITY OF WESTERN AUSTRALIA (AU) 2007-05-10 US disclosed
US-20070105721-A1 Vinylogous 4-Hpyrones and their use in promoting plant growth THE UNIVERSITY OF WESTERN AUSTRALIA (AU) 2007-05-10 US disclosed
US-20070105721-A1 Vinylogous 4-Hpyrones and their use in promoting plant growth THE UNIVERSITY OF WESTERN AUSTRALIA (AU) 2007-05-10 US disclosed
WO-2005061515-A1 VINYLOGOUS 4H-PYRONES AND THEIR USE IN PROMOTING PLANT GROWTH BOTANICAL GARDENS AND PARKS AUTHORITY (AU) 2005-07-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070105721-A1 Vinylogous 4-Hpyrones and their use in promoting plant growth HPD, MVD, FDPS MMP2 2256/4885ADORA2B 3897/4885TRPA1 2677/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.