Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C18 | P33260 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.37 |
| ▸ | SCN4A | P35499 | 2/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2628928 | 0.79 | CHRNB2 (0.47) | ALDH1A1KDM4ECHRNB2CHRNA4ADRB2 | |
| SCHEMBL9942581 | 0.78 | ALDH1A1 (0.40) | ALDH1A1KDM4EHDAC2HDAC3CHRNB2 | |
| SCHEMBL2629382 | 0.78 | DPP4 (0.44) | ALDH1A1KDM4ECHRNB2CHRNA4ADRB2 | |
| SCHEMBL3161903 | 0.78 | ADRB2 (0.46) | ALDH1A1KDM4ECHRNB2CHRNA4CYP1A2 | |
| SCHEMBL13044769 | 0.78 | SMN1; SMN2 (0.48) | ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL27237950 | 0.76 | ADRB2 (0.44) | ALDH1A1KDM4ECHRNB2CHRNA4CYP1A2 | |
| SCHEMBL7231518 | 0.75 | ALDH1A1 (0.70) | ALDH1A1KDM4EHDAC2HDAC3CHRNB2 | |
| SCHEMBL2828462 | 0.74 | KDR (0.53) | ALDH1A1KDM4E | |
| SCHEMBL2828246 | 0.74 | MLYCD (0.47) | — | |
| SCHEMBL28198368 | 0.74 | OGA (0.45) | ALDH1A1KDM4EHDAC2HDAC3CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099755-A2 | ACETYLENE DERIVATIVES AS STEAROYL COA DESATURASE INHIBITORS | Glenmark Pharmaceuticals S.A. (CH) | 2009-09-16 | — | — | EP | disclosed |
| US-20080182851-A1 | ACETYLENE DERIVATIVES AS STEAROYL COA DESATURASE INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2008-07-31 | — | — | US | disclosed |
| WO-2008062276-A2 | ACETYLENE DERIVATIVES AS STEAROYL COA DESATURASE INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (US) | 2008-05-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080182851-A1 | ACETYLENE DERIVATIVES AS STEAROYL COA DESATURASE INHIBITORS | SCD, SCD5, ACACA | ALDH1A1 578/4885KDM4E 1815/4885HDAC2 179/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.