Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOD1 | P00441 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PON1 | P27169 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17849169 | 0.94 | MAOA (0.30) | MAOAMAOBGRIN1GRIN2AGRIN2B | |
| SCHEMBL3842610 | 0.83 | MEN1 (0.37) | SOD1MEN1ALDH1A1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL3854115 | 0.81 | MAPK1 (0.36) | SOD1MEN1ALDH1A1KMT2AMAPT | |
| SCHEMBL12659928 | 0.81 | SOD1 (0.41) | SOD1ALDH1A1LMNAMAPT | |
| SCHEMBL13714459 | 0.80 | MEN1 (0.39) | SOD1MEN1KMT2AMAOAMAOB | |
| SCHEMBL3859983 | 0.78 | EGFR (0.30) | — | |
| SCHEMBL5154934 | 0.77 | MEN1 (0.37) | SOD1MEN1ALDH1A1KMT2ALMNA | |
| SCHEMBL1231689 | 0.77 | KDM4E (0.45) | MEN1ALDH1A1KMT2ALMNAMAPT | |
| Bromide SCHEMBL6271419 | 0.76 | MEN1 (0.38) | SOD1MEN1ALDH1A1KMT2ALMNA | |
| SCHEMBL1231730 | 0.76 | PON1 (0.34) | MEN1KMT2AMAPTPON1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2464424-B1 | DYE COMPOSITION COMPRISING A HETEROCYCLIC OXIDATION BASE AND AN INDOLE COUPLER | OREAL (FR) | 2019-09-25 | — | — | EP | claimed |
| EP-2651516-B1 | DYE COMPOSITION COMPRISING A HETEROCYCLIC OXIDATION BASE AND A 4-AMINOINDOLE COUPLER | L'ORÉAL (FR) | 2017-06-14 | — | — | EP | claimed |
| EP-2155153-B1 | DYEING COMPOSITION COMPRISING A SPECIFIC AMINOPYRAZOLOPYRIDINE OXIDATION BASE, A COUPLER AND A SPECIFIC SURFACTANT | L'ORÉAL (FR) | 2017-03-01 | — | — | EP | claimed |
| EP-2651935-B1 | DYEING COMPOSITION COMPRISING A FATTY SUBSTANCE, A PYRAZOLOPYRIDINE OXIDATION BASE AND A COUPLER | ORÉAL L (FR) | 2016-11-23 | — | — | EP | claimed |
| US-7578856-B2 | Dyeing compositions comprising at least one aminopyrazolopyridine oxidation base, at least one coupler and at least one C4-C30 polyol and methods and use thereof | L'OREAL S.A. (FR) | 2009-08-25 | — | — | US | claimed |
| EP-1992331-A1 | Dyeing composition comprising an aminopyrazolopyridine oxidation base, a coupler and a specific polyol | L'Oreal (FR) | 2008-11-19 | — | — | EP | claimed |
| EP-1992330-A2 | Process for colouring keratinous fibres comprising the application of an aminopyrazolopyridine oxidation base in the absence of oxidizing agent | L'Oreal (FR) | 2008-11-19 | — | — | EP | claimed |
| EP-1992329-A1 | Dyeing composition comprising an aminopyrazolopyridine oxidation base and a specific associative polymer | L'Oréal (FR) | 2008-11-19 | — | — | EP | claimed |
| US-11730688-B2 | Composition for dyeing the hair, comprising a heterocyclic oxidation base and a 2-amino-5-ethylphenol coupler | L'OREAL (FR) | 2023-08-22 | — | — | US | disclosed |
| EP-2464424-B1 | DYE COMPOSITION COMPRISING A HETEROCYCLIC OXIDATION BASE AND AN INDOLE COUPLER | OREAL (FR) | 2019-09-25 | — | — | EP | disclosed |
| EP-2464424-B1 | DYE COMPOSITION COMPRISING A HETEROCYCLIC OXIDATION BASE AND AN INDOLE COUPLER | OREAL (FR) | 2019-09-25 | — | — | EP | disclosed |
| US-20170354580-A1 | DYE COMPOSITION COMPRISING A PARA-PHENYLENEDIAMINE OXIDATION BASE AND A HETEROCYCLIC OXIDATION BASE | L'OREAL (FR) | 2017-12-14 | — | — | US | disclosed |
| EP-2651516-B1 | DYE COMPOSITION COMPRISING A HETEROCYCLIC OXIDATION BASE AND A 4-AMINOINDOLE COUPLER | L'ORÉAL (FR) | 2017-06-14 | — | — | EP | disclosed |
| EP-2155153-B1 | DYEING COMPOSITION COMPRISING A SPECIFIC AMINOPYRAZOLOPYRIDINE OXIDATION BASE, A COUPLER AND A SPECIFIC SURFACTANT | L'ORÉAL (FR) | 2017-03-01 | — | — | EP | disclosed |
| EP-1992331-A1 | Dyeing composition comprising an aminopyrazolopyridine oxidation base, a coupler and a specific polyol | L'Oreal (FR) | 2008-11-19 | — | — | EP | disclosed |
| EP-1992331-A1 | Dyeing composition comprising an aminopyrazolopyridine oxidation base, a coupler and a specific polyol | L'Oreal (FR) | 2008-11-19 | — | — | EP | disclosed |
| EP-1992330-A2 | Process for colouring keratinous fibres comprising the application of an aminopyrazolopyridine oxidation base in the absence of oxidizing agent | L'Oreal (FR) | 2008-11-19 | — | — | EP | disclosed |
| EP-1992330-A2 | Process for colouring keratinous fibres comprising the application of an aminopyrazolopyridine oxidation base in the absence of oxidizing agent | L'Oreal (FR) | 2008-11-19 | — | — | EP | disclosed |
| US-20070136959-A1 | Composition for dyeing keratin fibers comprising at least one cationic 3-amino-pyrazolopyridine derivative, and methods of use thereof | L'OREAL S.A. (FR) | 2007-06-21 | — | — | US | disclosed |
| EP-1792903-A1 | Composition for the dyeing of keratin fibres comprising at least one cationic 3-amino-pyrazolopyridine derivative | L'OREAL (FR) | 2007-06-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070136959-A1 | Composition for dyeing keratin fibers comprising at least one cationic 3-amino-pyrazolopyridine derivative, and methods of use thereof | KRT18, COX5A, PNPO | SOD1 1497/4885MEN1 4499/4885ALDH1A1 264/4885 |
| US-11730688-B2 | Composition for dyeing the hair, comprising a heterocyclic oxidation base and a 2-amino-5-ethylphenol coupler | KRT18, COX5B, COX5A | SOD1 3822/4885MEN1 4329/4885ALDH1A1 522/4885 |
| US-20170354580-A1 | DYE COMPOSITION COMPRISING A PARA-PHENYLENEDIAMINE OXIDATION BASE AND A HETEROCYCLIC OXIDATION BASE | KRT18, DSG1, SQOR | SOD1 842/4885MEN1 2015/4885ALDH1A1 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.