SCHEMBL3853892

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2499735	0.87	HDAC1 (0.45)	ALDH1A1HDAC1HDAC6SMN1; SMN2KMT2A
	SCHEMBL2477195	0.84	ALDH1A1 (0.49)	ALDH1A1MAPTHPGDHDAC1HDAC6
	SCHEMBL2470969	0.80	HDAC1 (0.52)	HDAC1HDAC6HDAC3HDAC2
	SCHEMBL3836368	0.78	HDAC1 (0.73)	ALDH1A1MAPTHPGDHDAC1HDAC6
	SCHEMBL3835157	0.77	GAA (0.51)	ALDH1A1MAPTHPGDHDAC1HDAC6
	SCHEMBL7459691	0.75	ALDH1A1 (0.59)	ALDH1A1SMN1; SMN2KMT2APPIDLPAR1
	SCHEMBL7188228	0.75	MAPT (0.58)	PKMALDH1A1MAPTHPGDHDAC1
	SCHEMBL9837067	0.73	ALDH1A1 (0.70)	ALDH1A1MAPTHPGDSMN1; SMN2RAB9A
	SCHEMBL1854059	0.73	MAPT (0.56)	PKMALDH1A1MAPTHPGDSMN1; SMN2
	SCHEMBL14488049	0.73	SMN1; SMN2 (0.63)	ALDH1A1MAPTHPGDSMN1; SMN2RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.