Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 6/20 | 0.49 |
| ▸ | FAAH | O00519 | 2/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.41 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.41 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.41 |
| ▸ | PLA2G2E | Q9NZK7 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3853093 | 0.91 | PLA2G2A (0.49) | PLA2G2APTGDR2ESR1PLA2G1BPLA2G10 | |
| SCHEMBL3860742 | 0.86 | FAAH (0.51) | FAAHPTGDR2MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL3853145 | 0.84 | SMN1; SMN2 (0.55) | PLA2G2APTGDR2ESR1MAPTSMN1; SMN2 | |
| SCHEMBL3854951 | 0.81 | ESR1 (0.46) | PLA2G2AFAAHESR1PLA2G10MAPT | |
| SCHEMBL3852008 | 0.81 | ESR1 (0.51) | PLA2G2AFAAHESR1 | |
| SCHEMBL3854607 | 0.81 | ESR1 (0.43) | PTGDR2ESR1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL3855188 | 0.80 | ESR1 (0.44) | PLA2G2APTGDR2ESR1MAPTALDH1A1 | |
| SCHEMBL3852458 | 0.76 | FABP4 (0.53) | PLA2G2APTGDR2PLA2G1BPLA2G10PLA2G5 | |
| SCHEMBL3854730 | 0.76 | ESR1 (0.39) | PTGDR2ESR1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL6795558 | 0.74 | ESR1 (0.51) | PLA2G2AESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582773-B2 | Substituted phenyl indoles | WYETH (US) | 2009-09-01 | — | — | US | disclosed |
| US-20050070592-A1 | Substituted phenyl indoles | WYETH (US) | 2005-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050070592-A1 | Substituted phenyl indoles | TPH2, IDO2, AANAT | PLA2G2A 3821/4885FAAH 792/4885PTGDR2 1104/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.