Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.40 |
| ▸ | TSPO | P30536 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3856618 | 0.83 | PPARG (0.51) | PLA2G2AKDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL3855495 | 0.83 | PLA2G2A (0.65) | PLA2G2AKDM4EALDH1A1KMT2APTGDR2 | |
| SCHEMBL13270705 | 0.82 | PTGDR2 (0.46) | PLA2G2AKDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL4223544 | 0.81 | KDM4E (0.56) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL3854596 | 0.78 | KDM4E (0.45) | PLA2G2AKDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL3854969 | 0.76 | KDM4E (0.46) | PLA2G2AKDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL18509730 | 0.74 | PLA2G4A (0.47) | PLA2G2AEGFRSRCTACR1PLA2G4A | |
| SCHEMBL3128263 | 0.73 | PLA2G4A (0.65) | PLA2G2AKDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL1050879 | 0.72 | SPR (0.44) | KDM4EALDH1A1KMT2ANPC1PLA2G4A | |
| SCHEMBL1923381 | 0.72 | GPR3 (0.64) | KDM4EALDH1A1HPGDKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582773-B2 | Substituted phenyl indoles | WYETH (US) | 2009-09-01 | — | — | US | disclosed |
| US-20050070592-A1 | Substituted phenyl indoles | WYETH (US) | 2005-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050070592-A1 | Substituted phenyl indoles | TPH2, IDO2, AANAT | PLA2G2A 3821/4885KDM4E 758/4885ALDH1A1 423/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.