Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 5/20 | 0.67 |
| ▸ | FABP4 | P15090 | 3/20 | 0.56 |
| ▸ | CA1 | P00915 | 3/20 | 0.55 |
| ▸ | CA2 | P00918 | 3/20 | 0.55 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3853519 | 0.85 | HTR6 (0.52) | HTR6FABP4CA1CA2PTGS1 | |
| SCHEMBL3853296 | 0.85 | CA1 (0.59) | HTR6FABP4CA1CA2PTGS1 | |
| SCHEMBL3852363 | 0.84 | FABP4 (0.53) | HTR6FABP4CA1CA2PTGS1 | |
| SCHEMBL3860461 | 0.84 | HTR6 (0.50) | HTR6FABP4CA1CA2PTGS1 | |
| SCHEMBL3853687 | 0.79 | HTR6 (0.45) | HTR6FABP4CA1CA2PTGS1 | |
| SCHEMBL3857090 | 0.78 | PTGS1 (0.56) | HTR6PTGS1PTGS2PTGDR2 | |
| SCHEMBL4726486 | 0.78 | KDM4E (0.52) | HTR6CA1CA2HRH1PTGDR2 | |
| SCHEMBL7464584 | 0.78 | CA1 (0.67) | HTR6FABP4CA1CA2PTGS1 | |
| SCHEMBL3854740 | 0.77 | TSHR (0.57) | — | |
| SCHEMBL3857256 | 0.77 | CA1 (0.65) | HTR6FABP4CA1CA2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582773-B2 | Substituted phenyl indoles | WYETH (US) | 2009-09-01 | — | — | US | disclosed |
| US-20050070592-A1 | Substituted phenyl indoles | WYETH (US) | 2005-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050070592-A1 | Substituted phenyl indoles | TPH2, IDO2, AANAT | HTR6 18/4885FABP4 3815/4885CA1 2159/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.