Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | F7 | P08709 | 1/20 | 0.40 |
| ▸ | F3 | P13726 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.39 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.39 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3855976 | 0.83 | CASP6 (0.54) | ALDH1A1TSHRTDP1MEN1MAPT | |
| SCHEMBL4960637 | 0.79 | ALDH1A1 (0.61) | ALDH1A1TSHRTDP1MEN1MAPT | |
| SCHEMBL3139020 | 0.73 | ALDH1A1 (0.39) | ALDH1A1TSHRTDP1MEN1MAPT | |
| SCHEMBL29720550 | 0.73 | TDP1 (0.70) | ALDH1A1TSHRTDP1MEN1MAPT | |
| SCHEMBL8653951 | 0.72 | S100A4 (0.52) | ALDH1A1TSHRTDP1MAPTKMT2A | |
| SCHEMBL6154941 | 0.72 | ALDH1A1 (0.43) | ALDH1A1TSHRTDP1MEN1MAPT | |
| SCHEMBL11841641 | 0.72 | ALDH1A1 (0.47) | ALDH1A1MAPTSMN1; SMN2POLB | |
| SCHEMBL31268201 | 0.71 | ALDH1A1 (0.63) | ALDH1A1TSHRTDP1MEN1MAPT | |
| SCHEMBL4962030 | 0.71 | ALDH1A1 (0.63) | ALDH1A1TSHRTDP1MEN1MAPT | |
| SCHEMBL8668528 | 0.70 | TSHR (0.66) | ALDH1A1TSHRTDP1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7579468-B2 | Methods of modulating neurotrophin-mediated activity | PAINCEPTOR PHARMA CORPORATION (CA) | 2009-08-25 | — | — | US | disclosed |
| EP-1931637-A2 | METHODS OF MODULATING NEUROTROPHIN-MEDIATED ACTIVITY | PainCeptor Pharma Corp. (CA) | 2008-06-18 | — | — | EP | disclosed |
| US-20070093474-A1 | Methods of modulating neurotrophin-mediated activity | PAINCEPTOR PHARMA CORPORATION (CA) | 2007-04-26 | — | — | US | disclosed |
| WO-2007030940-A2 | METHODS OF MODULATING NEUROTROPHIN-MEDIATED ACTIVITY | PAINCEPTOR PHARMA CORPORATION (CA) | 2007-03-22 | — | — | WO | disclosed |
| EP-0125439-B1 | 3,6-DISUBSTITUTED-1,8-NAPHTHALIMIDES AND METHODS FOR THEIR PRODUCTION AND USE | WARNER-LAMBERT COMPANY (US) | 1990-01-24 | — | — | EP | disclosed |
| US-4665071-A | ANTITUMOR AGENTS | WARNER-LAMBERT COMPANY (US) | 1987-05-12 | — | — | US | disclosed |
| US-4614820-A | ANTIMICROBIAL AND ANTITUMOR AGENTS | WARNER-LAMBERT CO. (US) | 1986-09-30 | — | — | US | disclosed |
| US-4594346-A | Antileukemia agent | WARNER-LAMBERT COMPANY (US) | 1986-06-10 | — | — | US | disclosed |
| US-4499266-A | MICROBIOCIDES AND ANTICARCINOGENIC | WARNER-LAMBERT COMPANY (US) | 1985-02-12 | — | — | US | disclosed |
| EP-0125439-A2 | 3,6-Disubstituted-1,8-naphthalimides and methods for their production and use | WARNER-LAMBERT COMPANY (US) | 1984-11-21 | — | — | EP | disclosed |
| US-4231799-A | MONOAZO DYES, MULTILAYER, CHARGE TRANSPORTING COMPOUND | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-11-04 | — | — | US | disclosed |
| US-4072520-A | ORGANIC DYES, XEROGRAPHY | HOECHST AKTIENGESELLSCHAFT (DT) | 1978-02-07 | — | — | US | disclosed |
| US-3996049-A | XEROGRAPHY | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-12-07 | — | — | US | disclosed |
| US-3989520-A | XEROGRAPHY | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-11-02 | — | — | US | disclosed |
| US-3977870-A | ORGANIC DYESTUFF LAYER | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070093474-A1 | Methods of modulating neurotrophin-mediated activity | NGF, BDNF, NTRK2 | ALDH1A1 2086/4885TSHR 972/4885TDP1 2055/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.