Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | LIPE | Q05469 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3858464 | 0.94 | THRB (0.46) | THRATHRBELANELIPEHPGD | |
| SCHEMBL6653843 | 0.81 | THRB (0.51) | THRATHRBELANEHPGDMEN1 | |
| SCHEMBL31711461 | 0.79 | THRB (0.50) | THRATHRBKMT2AMAPTCYP3A4 | |
| SCHEMBL6071880 | 0.79 | LMNA (0.57) | THRATHRBKMT2AMAPTCYP1A2 | |
| SCHEMBL3859415 | 0.79 | THRA (0.54) | THRATHRBELANECYP1A2CYP2C19 | |
| SCHEMBL16087039 | 0.79 | THRA (0.50) | THRATHRBHPGDMEN1KMT2A | |
| SCHEMBL10928698 | 0.79 | ELANE (0.50) | THRATHRBELANEMEN1KMT2A | |
| SCHEMBL9260093 | 0.79 | THRA (0.50) | THRATHRBMEN1KMT2AMAPT | |
| SCHEMBL505224 | 0.78 | THRA (0.49) | THRATHRBELANEHPGDMAPT | |
| SCHEMBL17573439 | 0.78 | ELANE (0.52) | THRATHRBELANEMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-58079954-A | — | — | None | — | — | JP | disclosed |
| CN-110498773-B | Method for synthesizing 1, 4-substituted 1,2, 3-triazole from acetylenic acid | 乐山师范学院 | 2021-07-02 | — | — | CN | disclosed |
| CN-107556269-B | Synthetic method of alpha-alkynyl substituted ether compound | 南京理工大学 | 2020-11-06 | — | — | CN | disclosed |
| CN-108424367-B | Method for preparing propiolic acid and derivatives thereof under mild condition | 中国科学院化学研究所 | 2020-08-18 | — | — | CN | disclosed |
| CN-104151278-B | The synthetic method of 1-phenyl-2,3-naphthalene dicarboxylic acids acid anhydride and derivative thereof | SHAANXI NORMAL UNIVERSITY (CN) | 2016-04-06 | — | — | CN | disclosed |
| CN-104151278-A | Synthesis method of 1-phenyl-2,3-naphthalene dicarboxylic anhydride and derivatives thereof | UNIV SHAANXI NORMAL | 2014-11-19 | — | — | CN | disclosed |
| US-20120202794-A1 | COMPOUNDS | PHARMASSET, INC. (US) | 2012-08-09 | — | — | US | disclosed |
| WO-2012103113-A1 | PYRAZINE AND IMIDAZOLIDINE DERIVATIVES AND THEIR USES TO TREAT HEPATITIS C | GILEAD PHARMASSET, LLC (US) | 2012-08-02 | — | — | WO | disclosed |
| US-7592373-B2 | Amide compounds with MCH antagonistic activity and medicaments comprising these compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-09-22 | — | — | US | disclosed |
| US-20050267093-A1 | Amide compounds with MCH antagonistic activity and medicaments comprising these compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-12-01 | — | — | US | disclosed |
| CN-1183133-C | 2-amino-6-anilino-purines and their use as medicaments | ��˹��ŵ�� | 2005-01-05 | — | — | CN | disclosed |
| CN-1340054-A | 2-amino-6-anilino-purines and their use as medicaments | NOVARTIS AG (CH) | 2002-03-13 | — | — | CN | disclosed |
| JP-S5879954-A | PROPIOLIC ACID ESTER COMPOUND | IHARA CHEM IND CO LTD | 1983-05-13 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120202794-A1 | COMPOUNDS | HAVCR2, MAVS, GOT2 | THRA 4493/4885THRB 4060/4885ELANE 235/4885 |
| US-20050267093-A1 | Amide compounds with MCH antagonistic activity and medicaments comprising these compounds | MCHR1, MC4R, MCHR2 | THRA 170/4885THRB 141/4885ELANE 2070/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.