Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | THRA | P10827 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | ACR | P10323 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3859415 | 0.83 | THRA (0.54) | LMNATHRATHRBALDH1A1GAA | |
| SCHEMBL4544923 | 0.83 | LMNA (0.61) | LMNAALDH1A1GAAKMT2ACYP1A2 | |
| SCHEMBL6653843 | 0.81 | THRB (0.51) | LMNATHRATHRBGAAKMT2A | |
| SCHEMBL10928698 | 0.79 | ELANE (0.50) | LMNATHRATHRBKMT2ARXFP1 | |
| SCHEMBL12314506 | 0.79 | LMNA (0.57) | LMNAALDH1A1GAAKMT2ACYP1A2 | |
| SCHEMBL16087039 | 0.79 | THRA (0.50) | THRATHRBALDH1A1KMT2ACYP1A2 | |
| SCHEMBL3864698 | 0.79 | THRA (0.50) | THRATHRBKMT2ACYP1A2CYP2C19 | |
| SCHEMBL31711461 | 0.79 | THRB (0.50) | LMNATHRATHRBALDH1A1GAA | |
| SCHEMBL9260093 | 0.79 | THRA (0.50) | LMNATHRATHRBALDH1A1KMT2A | |
| SCHEMBL14922470 | 0.79 | THRA (0.50) | THRATHRBALDH1A1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1183133-C | 2-amino-6-anilino-purines and their use as medicaments | ��˹��ŵ�� | 2005-01-05 | — | — | CN | claimed |
| CN-1340054-A | 2-amino-6-anilino-purines and their use as medicaments | NOVARTIS AG (CH) | 2002-03-13 | — | — | CN | claimed |
| CN-111203279-B | Sandwich nano material ZIF-8@Au 25 @ ZIF-67 and preparation method and application thereof | 安徽大学 | 2023-04-25 | — | — | CN | disclosed |
| CN-109438301-A | A kind of synthetic method of α-trifluoromethylthio substituted aroma ketone compounds | 江南大学 | 2019-03-08 | — | — | CN | disclosed |
| CN-104151278-B | The synthetic method of 1-phenyl-2,3-naphthalene dicarboxylic acids acid anhydride and derivative thereof | SHAANXI NORMAL UNIVERSITY (CN) | 2016-04-06 | — | — | CN | disclosed |
| CN-104151278-A | Synthesis method of 1-phenyl-2,3-naphthalene dicarboxylic anhydride and derivatives thereof | UNIV SHAANXI NORMAL | 2014-11-19 | — | — | CN | disclosed |
| US-20120202794-A1 | COMPOUNDS | PHARMASSET, INC. (US) | 2012-08-09 | — | — | US | disclosed |
| WO-2012103113-A1 | PYRAZINE AND IMIDAZOLIDINE DERIVATIVES AND THEIR USES TO TREAT HEPATITIS C | GILEAD PHARMASSET, LLC (US) | 2012-08-02 | — | — | WO | disclosed |
| US-20060160794-A1 | Tachykinin receptor antagonists | ELI LILLY AND COMPANY | 2006-07-20 | — | — | US | disclosed |
| CN-1183133-C | 2-amino-6-anilino-purines and their use as medicaments | ��˹��ŵ�� | 2005-01-05 | — | — | CN | disclosed |
| CN-1340054-A | 2-amino-6-anilino-purines and their use as medicaments | NOVARTIS AG (CH) | 2002-03-13 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120202794-A1 | COMPOUNDS | HAVCR2, MAVS, GOT2 | LMNA 4549/4885THRA 4493/4885THRB 4060/4885 |
| US-20060160794-A1 | Tachykinin receptor antagonists | TACR1, TACR2, PROKR1 | LMNA 4479/4885THRA 681/4885THRB 751/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.