SCHEMBL38656337

SCHEMBL38656337

COc1cc(-c2nc(CN3CCN(C)CC3)co2)ccc1[N+](=O)[O-]

nearest known ligand 0.49

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 5/20 0.49
ABCC1 P33527 3/20 0.49
SIRT6 Q8N6T7 1/20 0.49
POLB P06746 1/20 0.47
DRD2 P14416 4/20 0.44
DRD4 P21917 4/20 0.44
DRD3 P35462 4/20 0.44
HRH3 Q9Y5N1 1/20 0.41
MAPT P10636 1/20 0.41
CHEK1 O14757 1/20 0.41
ALDH1A1 P00352 1/20 0.41
CYP2D6 P10635 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL38657307 0.82 ABCB1 (0.53) ABCB1ABCC1DRD2DRD4DRD3
SCHEMBL38657597 0.81 SIRT6 (0.50) SIRT6POLBMAPTCHEK1ALDH1A1
SCHEMBL38656342 0.81 HTR7 (0.56) ABCB1ABCC1SIRT6DRD2DRD4
SCHEMBL38656222 0.81 CHEK1 (0.43) POLBMAPTCHEK1ALDH1A1
SCHEMBL38657531 0.78 ALDH1A1 (0.60) SIRT6POLBMAPTALDH1A1L3MBTL1
SCHEMBL29282830 0.77 SIRT6 (0.50) SIRT6POLBDRD2DRD4DRD3
SCHEMBL30930754 0.77 SIRT6 (0.50) SIRT6POLBDRD2DRD4DRD3
SCHEMBL10291110 0.76 SIRT6 (0.62) SIRT6MAPTALDH1A1CYP2D6L3MBTL1
SCHEMBL30019164 0.76 SIRT6 (0.62) SIRT6MAPTALDH1A1CYP2D6L3MBTL1
SCHEMBL38657436 0.75 SIRT6 (0.50) ABCB1ABCC1SIRT6POLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122036715-A 2, 4-Diarylaminopyrimidine derivative containing benzodithioryl, and pharmaceutical composition and application thereof 盐城工业职业技术学院 2026-05-15 CN disclosed