SCHEMBL38657307

SCHEMBL38657307

COc1cc(-c2nc(CN3CCN(C)CC3)co2)ccc1N

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 5/20 0.53
ABCC1 P33527 3/20 0.53
DRD2 P14416 5/20 0.48
DRD4 P21917 4/20 0.48
DRD3 P35462 4/20 0.48
HRH3 Q9Y5N1 2/20 0.45
ALDH1A1 P00352 1/20 0.41
CYP3A4 P08684 1/20 0.41
TSHR P16473 1/20 0.41
HSD17B10 Q99714 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
TGFBR1 P36897 1/20 0.41
ACVR1 Q04771 1/20 0.41
MTNR1A P48039 1/20 0.40
HTR2A P28223 1/20 0.39
HRH1 P35367 1/20 0.39
CDK2 P24941 1/20 0.39
PRKCZ Q05513 1/20 0.39
LMNA P02545 1/20 0.39
MAPT P10636 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL38656337 0.82 ABCB1 (0.49) ABCB1ABCC1DRD2DRD4DRD3
SCHEMBL38656807 0.79 HTR7 (0.61) ABCB1ABCC1DRD2DRD4DRD3
SCHEMBL2766091 0.78 DRD2 (0.52) ABCB1ABCC1DRD2DRD4DRD3
SCHEMBL3071421 0.76 ABCB1 (0.55) ABCB1ABCC1DRD2DRD4DRD3
SCHEMBL2764403 0.75 DRD2 (0.49) ABCB1ABCC1DRD2DRD4DRD3
SCHEMBL30930756 0.74 DRD2 (0.48) DRD2DRD4DRD3ALDH1A1CYP3A4
SCHEMBL29959053 0.73 LMNA (0.57) ALDH1A1HSD17B10TGFBR1ACVR1LMNA
SCHEMBL520829 0.73 LMNA (0.57) ALDH1A1HSD17B10TGFBR1ACVR1LMNA
SCHEMBL3087050 0.72 HRH3 (0.57) ABCB1ABCC1DRD2DRD4DRD3
SCHEMBL38657418 0.72 ALDH1A1 (0.42) HRH3ALDH1A1CYP3A4TSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122036715-A 2, 4-Diarylaminopyrimidine derivative containing benzodithioryl, and pharmaceutical composition and application thereof 盐城工业职业技术学院 2026-05-15 CN disclosed