SCHEMBL38656342

SCHEMBL38656342

COc1cc(-c2nc(CN3CCN(C)CC3)cs2)ccc1[N+](=O)[O-]

nearest known ligand 0.56

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HTR7 P34969 3/20 0.56
SIRT6 Q8N6T7 1/20 0.50
ABCB1 P08183 5/20 0.48
ABCC1 P33527 3/20 0.48
ABCG2 Q9UNQ0 1/20 0.48
ENPP2 Q13822 1/20 0.48
MET P08581 1/20 0.46
ROS1 P08922 1/20 0.46
ALK Q9UM73 1/20 0.46
KDM4E B2RXH2 2/20 0.46
ALDH1A1 P00352 2/20 0.46
GAA P10253 1/20 0.46
HPGD P15428 1/20 0.46
TDP1 Q9NUW8 1/20 0.45
DRD2 P14416 3/20 0.44
DRD4 P21917 3/20 0.44
DRD3 P35462 3/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6199911 0.85 HTR7 (0.74) HTR7ABCB1ABCC1ABCG2ENPP2
SCHEMBL38656807 0.82 HTR7 (0.61) HTR7ABCB1ABCC1ABCG2ENPP2
SCHEMBL38657436 0.82 SIRT6 (0.50) SIRT6ABCB1ABCC1KDM4EALDH1A1
SCHEMBL38655983 0.82 KDM4E (0.67) HTR7KDM4EALDH1A1GAAHPGD
SCHEMBL38656337 0.81 ABCB1 (0.49) SIRT6ABCB1ABCC1ALDH1A1DRD2
SCHEMBL30930754 0.78 SIRT6 (0.50) SIRT6ALDH1A1DRD2DRD4DRD3
SCHEMBL29282830 0.78 SIRT6 (0.50) SIRT6ALDH1A1DRD2DRD4DRD3
SCHEMBL38657531 0.77 ALDH1A1 (0.60) SIRT6KDM4EALDH1A1GAA
SCHEMBL30019164 0.77 SIRT6 (0.62) SIRT6KDM4EALDH1A1TDP1
SCHEMBL10291110 0.77 SIRT6 (0.62) SIRT6KDM4EALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122036715-A 2, 4-Diarylaminopyrimidine derivative containing benzodithioryl, and pharmaceutical composition and application thereof 盐城工业职业技术学院 2026-05-15 CN disclosed