SCHEMBL38656807

SCHEMBL38656807

COc1cc(-c2nc(CN3CCN(C)CC3)cs2)ccc1N

nearest known ligand 0.61

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HTR7 P34969 3/20 0.61
ABCB1 P08183 5/20 0.53
ABCC1 P33527 3/20 0.53
ABCG2 Q9UNQ0 1/20 0.53
ENPP2 Q13822 1/20 0.49
KDM4E B2RXH2 3/20 0.49
ALDH1A1 P00352 3/20 0.49
TDP1 Q9NUW8 1/20 0.49
DRD2 P14416 4/20 0.47
DRD4 P21917 4/20 0.47
DRD3 P35462 4/20 0.47
GAA P10253 1/20 0.47
HPGD P15428 1/20 0.47
MET P08581 1/20 0.47
ROS1 P08922 1/20 0.47
ALK Q9UM73 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6199911 0.90 HTR7 (0.74) HTR7ABCB1ABCC1ABCG2ENPP2
SCHEMBL38656342 0.82 HTR7 (0.56) HTR7ABCB1ABCC1ABCG2ENPP2
SCHEMBL38657418 0.80 ALDH1A1 (0.42) HTR7ALDH1A1TDP1GAA
SCHEMBL38657307 0.79 ABCB1 (0.53) ABCB1ABCC1ALDH1A1TDP1DRD2
SCHEMBL2766572 0.78 HTR7 (0.61) HTR7ABCB1ABCC1ABCG2KDM4E
SCHEMBL30930756 0.75 DRD2 (0.48) ALDH1A1TDP1DRD2DRD4DRD3
SCHEMBL22221690 0.75 DRD2 (0.78) HTR7ENPP2KDM4EDRD2DRD4
SCHEMBL2765186 0.75 HTR7 (0.57) HTR7ABCB1ABCC1ABCG2KDM4E
SCHEMBL29959053 0.73 LMNA (0.57) HTR7ALDH1A1
SCHEMBL520829 0.73 LMNA (0.57) HTR7ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122036715-A 2, 4-Diarylaminopyrimidine derivative containing benzodithioryl, and pharmaceutical composition and application thereof 盐城工业职业技术学院 2026-05-15 CN disclosed