SCHEMBL38664288

SCHEMBL38664288

CC(C)(C)ONN(C(=O)NN)S(=O)(=O)c1ccc(C(C)(C)O)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR1I2 O75469 1/20 0.36
HSD11B1 P28845 2/20 0.35
LMNA P02545 2/20 0.33
HTT P42858 2/20 0.33
MMP9 P14780 1/20 0.33
MMP13 P45452 1/20 0.33
PTGES O14684 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
ALDH1A1 P00352 2/20 0.33
ABCC9 O60706 2/20 0.32
ABCC8 Q09428 2/20 0.32
KCNJ11 Q14654 2/20 0.32
KCNJ8 Q15842 2/20 0.32
BMP1 P13497 1/20 0.32
TP53 P04637 1/20 0.32
TRPV4 Q9HBA0 1/20 0.32
MEN1 O00255 1/20 0.32
MAPT P10636 1/20 0.32
RECQL P46063 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL38666046 0.89 TRPV4 (0.36) HSD11B1LMNAHTTMMP9MMP13
SCHEMBL38663087 0.87 PTGES (0.44) LMNAHTTPTGESALDH1A1TP53
SCHEMBL38665422 0.86 PTGES (0.46) LMNAMMP9MMP13PTGESALDH1A1
SCHEMBL38666395 0.84 ALDH1A1 (0.40) LMNAMMP9MMP13PTGESALDH1A1
SCHEMBL38663856 0.82 BMP1 (0.34) LMNAHTTMMP13PTGESSMN1; SMN2
SCHEMBL38663830 0.82 HTT (0.32) LMNAHTTMMP9MMP13PTGES
SCHEMBL38666690 0.82 CA12 (0.38) LMNAHTTMMP9MMP13PTGES
SCHEMBL38664997 0.81 DAGLA (0.42) LMNASMN1; SMN2ALDH1A1MAPT
SCHEMBL38666420 0.81 LMNA (0.33) LMNAHTTPTGESSMN1; SMN2ALDH1A1
SCHEMBL38664976 0.80 SOS1 (0.38) HSD11B1LMNAHTTMMP9MMP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026104679-A1 NOVEL SULFONAMIDE DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2026-05-21 WO disclosed