SCHEMBL38664997

SCHEMBL38664997

CC(C)(C)ONN(C(=O)NN)S(=O)(=O)c1ccc(OC(F)F)cc1

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
DAGLA Q9Y4D2 6/20 0.42
MAPT P10636 3/20 0.41
ALDH1A1 P00352 6/20 0.38
LMNA P02545 4/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
ALOX15 P16050 1/20 0.36
GFER P55789 1/20 0.36
ADAM17 P78536 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
MMP3 P08254 1/20 0.35
KDM4E B2RXH2 1/20 0.34
RORC P51449 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL38663830 0.87 HTT (0.32) DAGLAMAPTALDH1A1LMNASMN1; SMN2
SCHEMBL38665422 0.85 PTGES (0.46) ALDH1A1LMNA
SCHEMBL38665413 0.84 MAPT (0.33) DAGLAMAPTALDH1A1LMNAADAM17
SCHEMBL38663841 0.84 MMP13 (0.32) DAGLAADAM17MMP3
SCHEMBL38663087 0.84 PTGES (0.44) MAPTALDH1A1LMNA
SCHEMBL38666395 0.83 ALDH1A1 (0.40) MAPTALDH1A1LMNAADAM17MMP3
SCHEMBL38666046 0.83 TRPV4 (0.36) ALDH1A1LMNASMN1; SMN2MMP3
SCHEMBL38666697 0.83 CA1 (0.33) DAGLAMMP3KDM4E
SCHEMBL38663856 0.82 BMP1 (0.34) ALDH1A1LMNASMN1; SMN2TDP1
SCHEMBL38664288 0.81 NR1I2 (0.36) MAPTALDH1A1LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026104679-A1 NOVEL SULFONAMIDE DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2026-05-21 WO disclosed
WO-2026104681-A1 NEW SULFONAMIDE DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2026-05-21 WO disclosed