Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSIP1 | O75475 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL777886 | 0.73 | PSIP1 (0.64) | PSIP1KEAP1NFE2L2HDAC1HDAC8 | |
| SCHEMBL10629823 | 0.72 | PSIP1 (0.61) | PSIP1KMT2AMEN1KEAP1NFE2L2 | |
| SCHEMBL576918 | 0.72 | KEAP1 (0.63) | PSIP1HTR7KMT2AMEN1KEAP1 | |
| Benzene SCHEMBL6390523 | 0.71 | PSIP1 (0.61) | PSIP1KEAP1NFE2L2HDAC1HDAC8 | |
| SCHEMBL2445501 | 0.71 | PSIP1 (0.61) | PSIP1KEAP1NFE2L2HDAC1HDAC8 | |
| SCHEMBL10626503 | 0.70 | HDAC1 (0.65) | PSIP1HTR7KMT2AMEN1KEAP1 | |
| SCHEMBL10616984 | 0.70 | PSIP1 (0.59) | PSIP1KEAP1NFE2L2HDAC1HDAC8 | |
| SCHEMBL5963682 | 0.70 | PSIP1 (0.59) | PSIP1KEAP1NFE2L2HDAC1HDAC8 | |
| SCHEMBL6673936 | 0.70 | PSIP1 (0.59) | PSIP1KEAP1NFE2L2HDAC1HDAC8 | |
| SCHEMBL16087603 | 0.70 | PSIP1 (0.59) | PSIP1KEAP1NFE2L2HDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7563924-B2 | 9-chloro-15-deoxyprostaglandin derivatives, process for their preparation and their use as medicaments | SCHERING AKTIENGESELLSCHAFT (DE) | 2009-07-21 | — | — | US | disclosed |
| EP-1816121-B1 | 9-Chloro-15-deoxyprostaglandin derivatives, process for their preparation and their use as medicaments | BAYER SCHERING PHARMA AG (DE) | 2008-03-12 | — | — | EP | disclosed |
| US-20070203096-A1 | 9-Chloro-15-deoxyprostaglandin derivatives, process for their preparation and their use as medicaments | SCHERING AKTIENGESELLSCHAFT (DE) | 2007-08-30 | — | — | US | disclosed |
| EP-1816121-A1 | 9-Chloro-15-deoxyprostaglandin derivatives, process for their preparation and their use as medicaments | Bayer Schering Pharma Aktiengesellschaft (DE) | 2007-08-08 | — | — | EP | disclosed |
| WO-2007057232-A1 | 9-CHLORO-15-DEOXYPROSTAGLANDIN DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-05-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070203096-A1 | 9-Chloro-15-deoxyprostaglandin derivatives, process for their preparation and their use as medicaments | PGF, PTGIS, CYP11B2 | PSIP1 2407/4885HTR7 341/4885KMT2A 4454/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.