Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 8/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1259250 | 0.94 | SLC9A1 (0.44) | SLC9A1KEAP1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL14353270 | 0.78 | TSHR (0.41) | SLC9A1KEAP1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL16564463 | 0.71 | TSHR (0.45) | SLC9A1KEAP1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL4822446 | 0.69 | KMT2A (0.42) | SLC9A1KEAP1ALDH1A1MAPTPOLB | |
| SCHEMBL29788159 | 0.67 | SLC9A1 (0.57) | SLC9A1KEAP1MAPTPOLBTSHR | |
| SCHEMBL598226 | 0.67 | DGAT1 (0.49) | SLC9A1ALDH1A1MAPTDGAT1POLB | |
| SCHEMBL4859508 | 0.66 | TSHR (0.50) | SLC9A1KEAP1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL14272188 | 0.65 | SLC9A1 (0.50) | SLC9A1KEAP1ALDH1A1CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL4990356 | 0.64 | RAB9A (0.51) | SLC9A1KEAP1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL3518163 | 0.64 | SLC9A1 (0.48) | SLC9A1KEAP1ALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9833768-B2 | Affinity reagents for protein purification | IMPOSSIBLE FOODS INC. (US) | 2017-12-05 | — | — | US | disclosed |
| US-20170320041-A1 | AFFINITY REAGENTS FOR PROTEIN PURIFICATION | IMPOSSIBLE FOODS INC. | 2017-11-09 | — | — | US | disclosed |
| US-9737875-B2 | Affinity reagents for protein purification | IMPOSSIBLE FOODS INC. (US) | 2017-08-22 | — | — | US | disclosed |
| US-20160222054-A1 | PH SWITCHABLE REAGENTS AND METHODS FOR THEIR USE | IMPOSSIBLE FOODS INC (US) | 2016-08-04 | — | — | US | disclosed |
| US-20150087532-A1 | AFFINITY REAGENTS FOR PROTEIN PURIFICATION | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2015-03-26 | — | — | US | disclosed |
| US-7479472-B1 | DNA-templated combinatorial library chemistry | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2009-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150087532-A1 | AFFINITY REAGENTS FOR PROTEIN PURIFICATION | RAB5IF, MRPL21, RPS27A | SLC9A1 4497/4885KEAP1 2336/4885ALDH1A1 4248/4885 |
| US-20160222054-A1 | PH SWITCHABLE REAGENTS AND METHODS FOR THEIR USE | PHPT1, CA6, HMBS | SLC9A1 1139/4885KEAP1 4120/4885ALDH1A1 1909/4885 |
| US-20170320041-A1 | AFFINITY REAGENTS FOR PROTEIN PURIFICATION | RAB5IF, MRPL21, RPS27A | SLC9A1 4497/4885KEAP1 2336/4885ALDH1A1 4248/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.