SCHEMBL3869162

SCHEMBL3869162

CCCCOc1ccc2c(c1)-c1ccccc1[N]2

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 2/20 0.46
PDK2 Q15119 3/20 0.45
PTPN11 Q06124 1/20 0.45
KMT2A Q03164 2/20 0.43
MEN1 O00255 1/20 0.43
NPC1 O15118 1/20 0.43
ALDH1A1 P00352 1/20 0.43
GAA P10253 1/20 0.43
MAPT P10636 1/20 0.43
RAB9A P51151 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
CYP1A2 P05177 2/20 0.43
CYP19A1 P11511 2/20 0.43
CYP2C9 P11712 2/20 0.43
CYP2C19 P33261 2/20 0.43
CYP2D6 P10635 2/20 0.43
FGFR1 P11362 1/20 0.43
PTPN1 P18031 1/20 0.42
GPBAR1 Q8TDU6 1/20 0.42
CYSLTR2 Q9NS75 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3868745 0.95 PTPN11 (0.51) LTA4HPDK2PTPN11PTPN1GPBAR1
SCHEMBL3868820 0.95 PTPN11 (0.51) LTA4HPDK2PTPN11PTPN1GPBAR1
SCHEMBL3870558 0.87 L3MBTL1 (0.47) LTA4HPDK2NPC1ALDH1A1MAPT
SCHEMBL3876767 0.78 CYP1A2 (0.45) PDK2KMT2AMEN1NPC1ALDH1A1
SCHEMBL18015983 0.73 MAPT (0.69) PDK2PTPN11KMT2AMEN1NPC1
SCHEMBL3879642 0.73 PDK2 (0.42) PDK2KMT2AMEN1NPC1ALDH1A1
SCHEMBL3879614 0.73 GPR3 (0.52) ALDH1A1CYP3A4
SCHEMBL14288507 0.72 MAPT (0.72) PTPN11KMT2AMEN1NPC1ALDH1A1
SCHEMBL5316394 0.72 HCAR2 (0.40) PDK2KMT2AMEN1ALDH1A1
SCHEMBL27670055 0.71 PTPN1 (0.58) LTA4HPDK2PTPN11KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2657315-B1 ORGANIC LIGHT-EMITTING DEVICE LG CHEMICAL LTD (KR) 2020-12-16 EP disclosed
CN-103562342-B Organic light emitting device and method of manufacturing the same 株式会社LG化学 2017-02-15 CN disclosed
US-9349964-B2 Organic light emitting diode and manufacturing method thereof LG CHEM, LTD. (KR) 2016-05-24 US disclosed
EP-2657315-A2 ORGANIC LIGHT-EMITTING DEVICE AND METHOD FOR MANUFACTURING SAME LG Chem, Ltd. (KR) 2013-10-30 EP disclosed
US-20120193612-A1 ORGANIC LIGHT EMITTING DIODE AND MANUFACTURING METHOD THEREOF LG CHEM, LTD. (KR) 2012-08-02 US disclosed
US-7482490-B2 Amine compound having fluorene group as framework, process for producing the amine compound, and use of the amine compound TOSOH CORPORATION (JP) 2009-01-27 US disclosed
US-20080194878-A1 Amine Compound Having Fluorene Group as Framework, Process for Producing the Amine Compound, and Use of the Amine Compound TOSOH CORPORATION (JP) 2008-08-14 US disclosed
US-7189877-B2 Arylamine derivatives having fluorene skeleton, synthetic intermediates thereof, processes of producing those, and organic electrolumivescene devices TOSCH CORPORATION (JP) 2007-03-13 US disclosed
EP-1752440-A1 AMINE COMPOUND HAVING FLUORENE GROUP AS FRAMEWORK, PROCESS FOR PRODUCING THE AMINE COMPOUND, AND USE OF THE AMINE COMPOUND Tosoh Corporation (JP) 2007-02-14 EP disclosed
EP-1400578-B1 Electrolumisescent 9,9-bis(4-amino)-1,1'-biphenyl)fluorene derivatives TOSOH CORP (JP) 2005-11-30 EP disclosed
US-20040110958-A1 Novel arylamine derivatives having fluorene skeleton, synthetic intermediates thereof, processes of producing those, and organic electrolumivescene devices TOSOH CORPORATION 2004-06-10 US disclosed
EP-1400578-A1 Electrolumisescent 9,9-bis(4-amino)-1,1'-biphenyl)fluorene derivatives Tosoh Corporation (JP) 2004-03-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040110958-A1 Novel arylamine derivatives having fluorene skeleton, synthetic intermediates thereof, processes of producing those, and organic electrolumivescene devices AHR, NAT1, AR LTA4H 1441/4885PDK2 2093/4885PTPN11 4529/4885
US-20080194878-A1 Amine Compound Having Fluorene Group as Framework, Process for Producing the Amine Compound, and Use of the Amine Compound TAAR1, SLC18A1, ADRB2 LTA4H 1727/4885PDK2 3867/4885PTPN11 4234/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.