SCHEMBL3879642

SCHEMBL3879642

CC(C)Oc1ccc2c(c1)-c1ccccc1[N]2

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 1/20 0.42
KMT2A Q03164 5/20 0.41
FGFR1 P11362 1/20 0.40
ALDH1A1 P00352 3/20 0.39
L3MBTL1 Q9Y468 1/20 0.38
MEN1 O00255 3/20 0.37
GAA P10253 2/20 0.37
MAPT P10636 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
NPC1 O15118 1/20 0.37
POLB P06746 1/20 0.37
PTGS1 P23219 1/20 0.37
SLC6A2 P23975 1/20 0.37
MAPK1 P28482 1/20 0.37
STAT1 P42224 1/20 0.37
CASP3 P42574 1/20 0.37
HTT P42858 1/20 0.37
RAB9A P51151 1/20 0.37
HIF1A Q16665 1/20 0.37
SENP8 Q96LD8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3876767 0.80 CYP1A2 (0.45) PDK2KMT2AALDH1A1L3MBTL1MEN1
SCHEMBL3870558 0.76 L3MBTL1 (0.47) PDK2ALDH1A1L3MBTL1MAPTSMN1; SMN2
SCHEMBL3869162 0.73 LTA4H (0.46) PDK2KMT2AFGFR1ALDH1A1L3MBTL1
SCHEMBL20553766 0.71 ABL1 (0.50) PDK2L3MBTL1MAPTSMN1; SMN2NPC1
SCHEMBL2962416 0.70 ELANE (0.47) PDK2KMT2AALDH1A1L3MBTL1MEN1
SCHEMBL24062 0.69 MEN1 (0.37) KMT2AALDH1A1L3MBTL1MEN1MAPT
SCHEMBL6897435 0.69 CA1 (0.40) KMT2AALDH1A1MEN1POLB
SCHEMBL20553770 0.69 LTA4H (0.56) KMT2AALDH1A1L3MBTL1MEN1MAPT
SCHEMBL16909647 0.69 CA1 (0.46) KMT2AALDH1A1MEN1MAPTSMN1; SMN2
SCHEMBL276584 0.67 CYP1A2 (0.58) KMT2AALDH1A1MEN1MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110473989-B Method for manufacturing organic light emitting element 株式会社LG化学 2022-05-27 CN disclosed
EP-2657315-B1 ORGANIC LIGHT-EMITTING DEVICE LG CHEMICAL LTD (KR) 2020-12-16 EP disclosed
CN-109923689-B Method for purifying organic substance used as material of organic light-emitting element 株式会社LG化学 2020-06-19 CN disclosed
US-9349964-B2 Organic light emitting diode and manufacturing method thereof LG CHEM, LTD. (KR) 2016-05-24 US disclosed
EP-2657315-A2 ORGANIC LIGHT-EMITTING DEVICE AND METHOD FOR MANUFACTURING SAME LG Chem, Ltd. (KR) 2013-10-30 EP disclosed
US-20120193612-A1 ORGANIC LIGHT EMITTING DIODE AND MANUFACTURING METHOD THEREOF LG CHEM, LTD. (KR) 2012-08-02 US disclosed
US-7482490-B2 Amine compound having fluorene group as framework, process for producing the amine compound, and use of the amine compound TOSOH CORPORATION (JP) 2009-01-27 US disclosed
US-20080194878-A1 Amine Compound Having Fluorene Group as Framework, Process for Producing the Amine Compound, and Use of the Amine Compound TOSOH CORPORATION (JP) 2008-08-14 US disclosed
US-7189877-B2 Arylamine derivatives having fluorene skeleton, synthetic intermediates thereof, processes of producing those, and organic electrolumivescene devices TOSCH CORPORATION (JP) 2007-03-13 US disclosed
EP-1752440-A1 AMINE COMPOUND HAVING FLUORENE GROUP AS FRAMEWORK, PROCESS FOR PRODUCING THE AMINE COMPOUND, AND USE OF THE AMINE COMPOUND Tosoh Corporation (JP) 2007-02-14 EP disclosed
EP-1400578-B1 Electrolumisescent 9,9-bis(4-amino)-1,1'-biphenyl)fluorene derivatives TOSOH CORP (JP) 2005-11-30 EP disclosed
US-20040110958-A1 Novel arylamine derivatives having fluorene skeleton, synthetic intermediates thereof, processes of producing those, and organic electrolumivescene devices TOSOH CORPORATION 2004-06-10 US disclosed
EP-1400578-A1 Electrolumisescent 9,9-bis(4-amino)-1,1'-biphenyl)fluorene derivatives Tosoh Corporation (JP) 2004-03-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040110958-A1 Novel arylamine derivatives having fluorene skeleton, synthetic intermediates thereof, processes of producing those, and organic electrolumivescene devices AHR, NAT1, AR PDK2 2093/4885KMT2A 1459/4885FGFR1 34/4885
US-20080194878-A1 Amine Compound Having Fluorene Group as Framework, Process for Producing the Amine Compound, and Use of the Amine Compound TAAR1, SLC18A1, ADRB2 PDK2 3867/4885KMT2A 2235/4885FGFR1 217/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.