SCHEMBL3876767

SCHEMBL3876767

COc1ccc2c(c1)-c1ccccc1[N]2

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.45
CYP2A6 P11509 1/20 0.45
GPR3 P46089 1/20 0.44
KDM4E B2RXH2 5/20 0.44
RAB9A P51151 4/20 0.44
ALDH1A1 P00352 4/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
NPC1 O15118 3/20 0.44
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
LMNA P02545 1/20 0.44
POLB P06746 1/20 0.44
NQO2 P16083 1/20 0.44
CYP2C9 P11712 3/20 0.43
CYP2C19 P33261 3/20 0.43
HTT P42858 1/20 0.43
ABL1 P00519 1/20 0.43
ABCB1 P08183 1/20 0.43
BCR P11274 1/20 0.43
MAPT P10636 5/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16909647 0.90 CA1 (0.46) CYP1A2CYP2A6KDM4ERAB9AALDH1A1
SCHEMBL3874584 0.89 GPR3 (0.49) CYP1A2CYP2A6GPR3KDM4ERAB9A
SCHEMBL20553766 0.86 ABL1 (0.50) RAB9ASMN1; SMN2NPC1ABL1ABCB1
SCHEMBL20553770 0.83 LTA4H (0.56) KDM4ERAB9AALDH1A1SMN1; SMN2NPC1
SCHEMBL20553960 0.81 LTA4H (0.46) GAA
SCHEMBL3879642 0.80 PDK2 (0.42) RAB9AALDH1A1SMN1; SMN2NPC1MEN1
SCHEMBL3870558 0.80 L3MBTL1 (0.47) KDM4ERAB9AALDH1A1SMN1; SMN2NPC1
SCHEMBL29086531 0.80 ALDH1A1 (0.51) KDM4ERAB9AALDH1A1SMN1; SMN2NPC1
SCHEMBL3869162 0.78 LTA4H (0.46) CYP1A2RAB9AALDH1A1NPC1MEN1
SCHEMBL29086596 0.77 KMT2A (0.50) RAB9ASMN1; SMN2NPC1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2657315-B1 ORGANIC LIGHT-EMITTING DEVICE LG CHEMICAL LTD (KR) 2020-12-16 EP disclosed
US-9349964-B2 Organic light emitting diode and manufacturing method thereof LG CHEM, LTD. (KR) 2016-05-24 US disclosed
EP-2657315-A2 ORGANIC LIGHT-EMITTING DEVICE AND METHOD FOR MANUFACTURING SAME LG Chem, Ltd. (KR) 2013-10-30 EP disclosed
US-20120193612-A1 ORGANIC LIGHT EMITTING DIODE AND MANUFACTURING METHOD THEREOF LG CHEM, LTD. (KR) 2012-08-02 US disclosed
US-7482490-B2 Amine compound having fluorene group as framework, process for producing the amine compound, and use of the amine compound TOSOH CORPORATION (JP) 2009-01-27 US disclosed
US-20080194878-A1 Amine Compound Having Fluorene Group as Framework, Process for Producing the Amine Compound, and Use of the Amine Compound TOSOH CORPORATION (JP) 2008-08-14 US disclosed
US-7189877-B2 Arylamine derivatives having fluorene skeleton, synthetic intermediates thereof, processes of producing those, and organic electrolumivescene devices TOSCH CORPORATION (JP) 2007-03-13 US disclosed
EP-1752440-A1 AMINE COMPOUND HAVING FLUORENE GROUP AS FRAMEWORK, PROCESS FOR PRODUCING THE AMINE COMPOUND, AND USE OF THE AMINE COMPOUND Tosoh Corporation (JP) 2007-02-14 EP disclosed
EP-1400578-B1 Electrolumisescent 9,9-bis(4-amino)-1,1'-biphenyl)fluorene derivatives TOSOH CORP (JP) 2005-11-30 EP disclosed
US-6824939-B2 PHOTORECEPTOR INCLUDING A PROTECTIVE LAYER INCLUDING A FILLER; PRODUCE HIGH QUALITY IMAGES FOR A LONG PERIOD OF TIME WITHOUT CAUSING DETERIORATION OF THE IMAGE RESOLUTION DUE TO SCATTERING OR DIFFUSE REFLECTION OF THE LASER LIGHT RICOH COMPANY LIMITED (JP) 2004-11-30 US disclosed
JP-2004315495-A NEW ARYLAMINE DERIVATIVE HAVING FLUORENE SKELETON, SYNTHETIC INTERMEDIATE OF THE SAME, METHOD FOR PRODUCING THEM AND ORGANIC EL ELEMENT TOSOH CORP 2004-11-11 JP disclosed
US-20040110958-A1 Novel arylamine derivatives having fluorene skeleton, synthetic intermediates thereof, processes of producing those, and organic electrolumivescene devices TOSOH CORPORATION 2004-06-10 US disclosed
EP-1400578-A1 Electrolumisescent 9,9-bis(4-amino)-1,1'-biphenyl)fluorene derivatives Tosoh Corporation (JP) 2004-03-24 EP disclosed
US-20030206226-A1 Electrophotographic image forming method and apparatus RICOH COMPANY LIMITED (JP) 2003-11-06 US disclosed
US-5364739-A Photocrosslinking, thermochromism BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1994-11-15 US disclosed
US-RE32162-E Pressure sensitive record material employing diaryl alkane solvents NIPPON PETROCHEMICALS CO., LTD. (JP) 1986-05-27 US disclosed
US-4289806-A DYE DISSOLVED IN SOLVENT OF AROMATIC HYDROCARBONS HAVING TWO OR THREE NON-CONDENSED BENZENE RINGS NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1981-09-15 US disclosed
US-4148968-A COLORLESS TONER, A POLYMER OR CLAY AND A FATTY ACID OR DERIVATIVE CANON KABUSHIKI KAISHA (JP) 1979-04-10 US disclosed
US-4054712-A ELECTROGRAPHY CANON KABUSHIKI KAISHA (JA) 1977-10-18 US disclosed
US-3936566-A Pressure sensitive record material employing diaryl alkane solvents NIPPON PETROCHEMICALS COMPANY LTD. (JA) 1976-02-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040110958-A1 Novel arylamine derivatives having fluorene skeleton, synthetic intermediates thereof, processes of producing those, and organic electrolumivescene devices AHR, NAT1, AR CYP1A2 22/4885CYP2A6 257/4885GPR3 370/4885
US-20080194878-A1 Amine Compound Having Fluorene Group as Framework, Process for Producing the Amine Compound, and Use of the Amine Compound TAAR1, SLC18A1, ADRB2 CYP1A2 312/4885CYP2A6 1015/4885GPR3 12/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.