Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | MMP7 | P09237 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 7/20 | 0.38 |
| ▸ | CES1 | P23141 | 4/20 | 0.38 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 6/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 6/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 6/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3869386 | 0.81 | CTSS (0.35) | ALDH1A1RAB9A | |
| SCHEMBL3872602 | 0.79 | LIPG (0.32) | ALDH1A1RAB9AHDAC3HDAC1HDAC6 | |
| SCHEMBL3871936 | 0.79 | CNR2 (0.33) | ALDH1A1RAB9A | |
| SCHEMBL3871979 | 0.79 | FAAH (0.45) | FAAHCES1RAB9A | |
| SCHEMBL3874379 | 0.76 | PRSS1 (0.33) | ALDH1A1RAB9AHDAC4HDAC1HDAC7 | |
| SCHEMBL3873933 | 0.75 | SMYD3 (0.36) | FAAHALDH1A1RAB9A | |
| SCHEMBL3870467 | 0.73 | MMP1 (0.43) | MMP1MMP2MMP3MMP7FAAH | |
| SCHEMBL3870014 | 0.73 | FAAH (0.40) | FAAHCES1HDAC3HDAC4HDAC1 | |
| SCHEMBL3969450 | 0.71 | DCAF1 (0.35) | HDAC1HDAC8HDAC6 | |
| SCHEMBL6207048 | 0.66 | CYP2C19 (0.48) | FAAHCES1NCEH1HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7482448-B2 | Compounds and compositions as cathepsin inhibitors | AVENTIS PHARMACEUTICALS INC. (US) | 2009-01-27 | — | — | US | disclosed |
| US-20060189657-A1 | Novel compounds and compositions as cathepsin inhibitors | AVENTIS PHARMACEUTICALS INC. (US) | 2006-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060189657-A1 | Novel compounds and compositions as cathepsin inhibitors | CTSB, CTSS, CTSK | MMP1 683/4885MMP2 139/4885MMP3 181/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.