Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 8/20 | 0.34 |
| ▸ | CTSL | P07711 | 5/20 | 0.33 |
| ▸ | CTSB | P07858 | 5/20 | 0.33 |
| ▸ | CTSH | P09668 | 4/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14294475 | 0.89 | TSHR (0.38) | TSHRALDH1A1CTSKCTSLCTSB | |
| SCHEMBL6721751 | 0.79 | TSHR (0.35) | TSHRCTSKCTSLCTSBCTSH | |
| SCHEMBL463743 | 0.78 | CTSK (0.36) | TSHRALDH1A1CTSKCTSLCTSB | |
| SCHEMBL4950381 | 0.75 | ALDH1A1 (0.44) | TSHRALDH1A1CTSKCTSLCTSB | |
| SCHEMBL8393350 | 0.74 | ALDH1A1 (0.42) | TSHRALDH1A1 | |
| SCHEMBL970597 | 0.74 | ALDH1A1 (0.54) | TSHRALDH1A1CTSKCTSLCTSB | |
| SCHEMBL12431464 | 0.71 | TSHR (0.39) | TSHRALDH1A1 | |
| SCHEMBL1820168 | 0.71 | HSD11B1 (0.37) | TSHRALDH1A1 | |
| SCHEMBL16326515 | 0.70 | TSHR (0.35) | TSHRALDH1A1 | |
| SCHEMBL91327 | 0.69 | TSHR (0.36) | TSHRALDH1A1CTSKCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7521169-B2 | Radiation-sensitive resin composition | JSR CORPORATION (JP) | 2009-04-21 | — | — | US | disclosed |
| US-20060234153-A1 | Radiation-sensitive resin composition | JSR CORPORATION (JP) | 2006-10-19 | — | — | US | disclosed |