SCHEMBL3874256

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3869026	0.90	CYP2C9 (0.72)	CYP2C9LMNATP53ALDH1A1MEN1
	SCHEMBL3870350	0.89	LMNA (0.54)	CYP2C9LMNATP53ALDH1A1MEN1
	SCHEMBL3873785	0.79	CYP2C9 (0.63)	CYP2C9LMNATP53ALDH1A1MEN1
	SCHEMBL3876121	0.74	CA2 (0.66)	CYP2C9LMNATP53ALDH1A1MEN1
	SCHEMBL12791371	0.72	TP53 (0.60)	CYP2C9LMNATP53ALDH1A1MEN1
	SCHEMBL3461102	0.70	NPC1 (0.70)	CYP2C9TP53ALDH1A1MEN1KMT2A
	SCHEMBL15766067	0.69	TGM2 (0.59)	LMNAALDH1A1MEN1KMT2ASMN1; SMN2
	SCHEMBL265806	0.69	MMP13 (0.59)	LMNA
	SCHEMBL5332860	0.69	NPC1 (0.72)	CYP2C9MEN1KMT2ACYP1A2CYP3A4
	SCHEMBL3472086	0.68	THRB (0.75)	LMNAMEN1KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.