SCHEMBL3877540

SCHEMBL3877540

CC1(C)CC(OC(=O)C2CC3C=CC2C3)C(=O)O1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.37
KDM4E B2RXH2 2/20 0.37
LMNA P02545 1/20 0.37
POLB P06746 3/20 0.35
HSD17B10 Q99714 2/20 0.35
APEX1 P27695 1/20 0.35
RECQL P46063 1/20 0.35
BLM P54132 1/20 0.35
ESR2 Q92731 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
HPGD P15428 1/20 0.35
KMT2A Q03164 3/20 0.35
RAB9A P51151 1/20 0.34
THRB P10828 1/20 0.32
MAPK1 P28482 1/20 0.31
HSD11B1 P28845 2/20 0.31
MEN1 O00255 1/20 0.30
ALOX15 P16050 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL120085 0.75 ALDH1A1 (0.41) ALDH1A1KDM4ELMNAPOLBHSD17B10
SCHEMBL13409254 0.75 ALDH1A1 (0.41) ALDH1A1KDM4ELMNAPOLBHSD17B10
SCHEMBL3874344 0.74 ALDH1A1 (0.37) ALDH1A1KDM4ELMNAPOLBHSD17B10
SCHEMBL3873295 0.74 ALDH1A1 (0.37) ALDH1A1KDM4ELMNAPOLBHSD17B10
SCHEMBL4400474 0.74 LMNA (0.47) ALDH1A1KDM4ELMNAPOLBHSD17B10
SCHEMBL3881575 0.72 ALDH1A1 (0.37) ALDH1A1KDM4ELMNAPOLBHSD17B10
SCHEMBL398230 0.71 OPRK1 (0.36) ALDH1A1KDM4EPOLBL3MBTL1HSD11B1
SCHEMBL75458 0.70 LMNA (0.41) ALDH1A1KDM4ELMNAPOLBHSD17B10
SCHEMBL22789979 0.70 LMNA (0.41) ALDH1A1KDM4ELMNAPOLBHSD17B10
SCHEMBL29325973 0.70 ALDH1A1 (0.48) ALDH1A1KDM4ELMNAPOLBHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7521169-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2009-04-21 US disclosed
US-20060234153-A1 Radiation-sensitive resin composition JSR CORPORATION (JP) 2006-10-19 US disclosed
EP-1557718-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR Corporation (JP) 2005-07-27 EP disclosed