Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR3 | P49682 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PFKFB3 | Q16875 | 6/20 | 0.44 |
| ▸ | PFKFB4 | Q16877 | 6/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3872971 | 0.89 | NPC1 (0.48) | ALDH1A1L3MBTL1PFKFB3PFKFB4F10 | |
| SCHEMBL3874981 | 0.82 | PFKFB4 (0.51) | CXCR3ALDH1A1PFKFB3PFKFB4LMNA | |
| SCHEMBL3879417 | 0.82 | PFKFB3 (0.61) | L3MBTL1PFKFB3PFKFB4F10LMNA | |
| SCHEMBL3874308 | 0.82 | PFKFB4 (0.45) | CXCR3PFKFB3PFKFB4F10LMNA | |
| SCHEMBL3886211 | 0.81 | PFKFB4 (0.64) | PFKFB3PFKFB4F10 | |
| SCHEMBL3886517 | 0.81 | PFKFB3 (0.53) | CXCR3PFKFB3PFKFB4TP53 | |
| SCHEMBL3881241 | 0.80 | LSS (0.43) | CXCR3HTTGAAPFKFB3PFKFB4 | |
| SCHEMBL3873244 | 0.80 | HTT (0.51) | CXCR3HTTALDH1A1GAAL3MBTL1 | |
| SCHEMBL3873199 | 0.79 | PFKFB4 (0.48) | ALDH1A1L3MBTL1PFKFB3PFKFB4F10 | |
| SCHEMBL3882723 | 0.77 | ALDH1A1 (0.51) | CXCR3HTTALDH1A1GAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1814846-B1 | 11BETA-HSD1 INHIBITORS | EVOTEC AG (DE) | 2009-04-08 | — | — | EP | disclosed |
| US-20090069323-A1 | 11beta-hsdi inhibitors | EVOTEC AG (DE) | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069323-A1 | 11beta-hsdi inhibitors | HSD3B1, HSD3B2, HSD11B1 | CXCR3 706/4885HTT 4278/4885ALDH1A1 210/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.