Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3881153 | 0.87 | ALDH1A1 (0.51) | HTTALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL3872261 | 0.84 | ALDH1A1 (0.56) | HTTALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL3878752 | 0.80 | CXCR3 (0.46) | HTTALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL3872528 | 0.80 | MMP13 (0.50) | ALDH1A1LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL3883351 | 0.79 | MRGPRX4 (0.52) | ALDH1A1LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL3872830 | 0.79 | ROCK2 (0.46) | ALDH1A1LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL3878132 | 0.79 | HTT (0.58) | HTTALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL3882723 | 0.79 | ALDH1A1 (0.51) | HTTALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL3872847 | 0.78 | TP53 (0.48) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL3874660 | 0.78 | ROCK2 (0.49) | ALDH1A1LMNASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1814846-B1 | 11BETA-HSD1 INHIBITORS | EVOTEC AG (DE) | 2009-04-08 | — | — | EP | disclosed |
| US-20090069323-A1 | 11beta-hsdi inhibitors | EVOTEC AG (DE) | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069323-A1 | 11beta-hsdi inhibitors | HSD3B1, HSD3B2, HSD11B1 | HTT 4278/4885ALDH1A1 210/4885LMNA 2473/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.