Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ASPH | Q12797 | 1/20 | 0.42 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 2/20 | 0.42 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.42 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.40 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6265543 | 0.87 | ELANE (0.47) | KDM4EALDH1A1LMNAASPHKDM8 | |
| SCHEMBL14451006 | 0.87 | ELANE (0.47) | KDM4EALDH1A1LMNAASPHKDM8 | |
| SCHEMBL3879390 | 0.78 | TRPA1 (0.45) | CXCR2ALDH1A1LMNAHSD17B10TRPA1 | |
| SCHEMBL6265941 | 0.77 | ALDH1A1 (0.49) | ALDH1A1LMNAHPGDATMMAPT | |
| SCHEMBL7206671 | 0.76 | LTC4S (0.44) | LMNAAURKBGAA | |
| SCHEMBL3879342 | 0.76 | KDM4E (0.45) | CXCR2KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL28647773 | 0.74 | ALDH1A1 (0.44) | CXCR2KDM4EALDH1A1LMNAHSD17B10 | |
| SCHEMBL3879535 | 0.74 | TRPA1 (0.41) | CXCR2ALDH1A1LMNAHSD17B10TRPA1 | |
| SCHEMBL12269615 | 0.73 | NPSR1 (0.44) | KDM4EALDH1A1LMNAASPHKDM8 | |
| SCHEMBL6542646 | 0.72 | MEN1 (0.47) | KDM4EALDH1A1LMNAMAPTASPH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7589127-B2 | Aminoalkylphenols, methods of using and making the same | MERCK & CO., INC. (US) | 2009-09-15 | — | — | US | disclosed |
| US-20050234265-A1 | Aminoalkylphenols, methods of using and making the same | MERCK SHARP & DOHME LLC | 2005-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050234265-A1 | Aminoalkylphenols, methods of using and making the same | NPEPPS, PHOSPHO1, LNPEP | CXCR2 4729/4885KDM4E 443/4885ALDH1A1 1120/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.