Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTC4S | Q16873 | 1/20 | 0.44 |
| ▸ | KRAS | P01116 | 1/20 | 0.43 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6264989 | 0.80 | SOS1 (0.55) | KRASSOS1 | |
| SCHEMBL3879337 | 0.76 | CXCR2 (0.46) | LMNAGAAAURKB | |
| SCHEMBL3879390 | 0.72 | TRPA1 (0.45) | LMNAGAACYP1A2 | |
| SCHEMBL12871845 | 0.71 | ALDH1A1 (0.54) | LTC4SLMNAGAACYP1A2 | |
| SCHEMBL15540540 | 0.71 | ALDH1A1 (0.54) | LTC4SLMNAGAACYP1A2 | |
| SCHEMBL9089450 | 0.71 | CASR (0.54) | — | |
| SCHEMBL7206660 | 0.71 | CASR (0.54) | — | |
| SCHEMBL8518963 | 0.70 | LMNA (0.61) | LTC4SLMNAGAA | |
| SCHEMBL7263715 | 0.70 | LMNA (0.61) | LTC4SLMNAGAA | |
| SCHEMBL2934798 | 0.70 | LMNA (0.61) | LTC4SLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0907631-B1 | INORGANIC ION RECEPTOR-ACTIVE COMPOUNDS | NPS PHARMA INC (US) | 2003-06-18 | — | — | EP | disclosed |