Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6142328 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL2777881 | 0.93 | — | — | |
| Hydrochloric Acid SCHEMBL727852 | 0.93 | — | — | |
| Hydrochloric Acid SCHEMBL7564378 | 0.77 | MAOA (0.37) | — | |
| Hydrochloric Acid SCHEMBL2777393 | 0.75 | ALDH1A1 (0.30) | — | |
| Hydrochloric Acid SCHEMBL846609 | 0.75 | MEN1 (0.33) | — | |
| SCHEMBL4612542 | 0.70 | MEN1 (0.33) | — | |
| Hydrochloric Acid SCHEMBL6356342 | 0.70 | ADRA1A (0.35) | — | |
| Hydrochloric Acid SCHEMBL6465548 | 0.69 | MEN1 (0.35) | — | |
| Hydrochloric Acid SCHEMBL4446419 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 252 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7223822-B2 | Multiple catalyst and reactor system for olefin polymerization and polymers produced therefrom | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-05-29 | — | — | US | claimed |
| US-20040220359-A1 | Multiple catalyst and reactor system for olefin polymerization and polymers produced therefrom | EXXONMOBIL CHEMICAL PATENTS INC. | 2004-11-04 | — | — | US | claimed |
| US-6664351-B1 | Polymerizing using catalyst consisting of reaction product of mixture of racemic and meso isomers of stereorigid metallocene compound of transition metal with two cyclopentadienyl ligands connected by chemical bridge and activating cocatalyst | BASELL TECHNOLOGY COMPANY B.V. (NL) | 2003-12-16 | — | — | US | claimed |
| EP-0819695-B1 | Process for modifying the rac/meso ratio in a matallocene compound | BASELL POLYOLEFINE GMBH (DE) | 2003-04-09 | — | — | EP | claimed |
| EP-0643078-B1 | Process for the preparation of ethylene polymers and products obtained therefrom | BASELL POLYOLEFINE GMBH (DE) | 2003-01-22 | — | — | EP | claimed |
| EP-0821011-B1 | Process for the preparation of ethylene-based polymers | BASELL TECHNOLOGY CO BV (NL) | 2001-01-31 | — | — | EP | claimed |
| EP-0575875-B1 | Catalysts for the polymerization of olefins | MONTELL TECHNOLOGY COMPANY BV (NL) | 2000-08-09 | — | — | EP | claimed |
| EP-0821011-A2 | Process for the preparation of ethylene-based polymers and catalyst system used therein | Montell Technology Company bv (NL) | 1998-01-28 | — | — | EP | claimed |
| EP-0819695-A2 | Process for modifying the rac/meso ratio in a matallocene compound | Montell Technology Company bv (NL) | 1998-01-21 | — | — | EP | claimed |
| US-5585448-A | USING CYCLOPENTADIENYL LIGAND CONTAINING METALLOCENE CATALYST | MONTELL TECHNOLOGY COMPANY B.V. (NL) | 1996-12-17 | — | — | US | claimed |
| EP-0742799-A1 | ETHYLENE COPOLYMERS, PROCESS FOR THE PREPARATION OF ETHYLENE-BASED POLYMERS AND CATALYST SYSTEM USED THEREIN | Montell Technology Company bv (NL) | 1996-11-20 | — | — | EP | claimed |
| WO-1995035333-A2 | ETHYLENE COPOLYMERS, PROCESS FOR THE PREPARATION OF ETHYLENE-BASED POLYMERS AND CATALYST SYSTEM USED THEREIN | MONTELL TECHNOLOGY COMPANY B.V. (NL) | 1995-12-28 | — | — | WO | claimed |
| EP-0643078-A2 | Process for the preparation of ethylene polymers and products obtained therefrom | Montell Technology Company bv (NL) | 1995-03-15 | — | — | EP | claimed |
| EP-0366290-B1 | Process for producing olefin polymers | CHISSO CORP (JP) | 1994-06-29 | — | — | EP | claimed |
| EP-0575875-A2 | Catalysts for the polymerization of olefins | Montell Technology Company bv (NL) | 1993-12-29 | — | — | EP | claimed |
| EP-0366290-A2 | Process for producing olefin polymers | CHISSO CORPORATION (JP) | 1990-05-02 | — | — | EP | claimed |
| US-20230137384-A1 | ARTICLE OF MANUFACTURE COMPRISING LOCAL ANESTHETIC, BUFFER, AND GLYCOSAMINOGLYCAN IN SYRINGE WITH IMPROVED STABILITY | URIGEN PHARMACEUTICALS, INC. | 2023-05-04 | — | — | US | disclosed |
| US-20210283172-A1 | ARTICLE OF MANUFACTURE COMPRISING LOCAL ANESTHETIC, BUFFER, AND GLYCOSAMINOGLYCAN IN SYRINGE WITH IMPROVED STABILITY | URIGEN PHARMACEUTICALS, INC. | 2021-09-16 | — | — | US | disclosed |
| EP-0279863-A1 | CATALYST FOR POLYMERIZING ALPHA-OLEFIN AND POLYMERIZATION PROCESS | MITSUI CHEMICALS, INC. (JP) | 1988-08-31 | — | — | EP | disclosed |
| EP-0279586-A2 | Finely divided aluminoxane, process for producing same and its use | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1988-08-24 | — | — | EP | disclosed |